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    Rv3789 GtrA family protein [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886109, updated on 6-Oct-2023

    Summary

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    Gene symbol
    Rv3789
    Gene description
    GtrA family protein
    Locus tag
    Rv3789
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (4235374..4235739)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferase Neighboring gene hypothetical protein Neighboring gene decaprenylphosphoryl-beta-D-ribose oxidase Neighboring gene decaprenylphosphoryl-D-2-keto erythropentose reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria. Larrouy-Maumus G, et al. J Biol Chem, 2012 Nov 16. PMID 23038254, Free PMC Article
    2. GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis. Kolly GS, et al. J Bacteriol, 2015 Dec. PMID 26369580, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Deletion of rv3789 led to a reduction in arabinan content and to an accumulation of decaprenyl phospho-arabinose.
      Title: GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis.
    2. Rv3789 interacts in vivo with the galactosyltransferase that initiates the elongation of the galactan domain of AG.
      Title: A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    GtrA family protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      4235374..4235739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_218306.1 GtrA family protein [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_218306.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      R4M110
      Conserved Domains (1) summary
      COG2246
      Location:1 → 121
      GtrA; Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose) [Lipid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WMS9.1

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