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    Rsu1 Ras suppressor protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 20163, updated on 3-Dec-2024

    Summary

    Official Symbol
    Rsu1provided by MGI
    Official Full Name
    Ras suppressor protein 1provided by MGI
    Primary source
    MGI:MGI:103040
    See related
    Ensembl:ENSMUSG00000026727 AllianceGenome:MGI:103040
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RsuI; rsp-1
    Summary
    Acts upstream of or within Ras protein signal transduction and positive regulation of neural precursor cell proliferation. Predicted to be located in focal adhesion. Is expressed in brain; cerebral cortex ventricular layer; meninges; and telencephalon. Orthologous to human RSU1 (Ras suppressor protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 59.3), subcutaneous fat pad adult (RPKM 30.5) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rsu1 in Genome Data Viewer
    Location:
    2 A1; 2 9.73 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (13081778..13276116, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (13076967..13271438, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phosphotriesterase related Neighboring gene STARR-seq mESC enhancer starr_03698 Neighboring gene predicted gene, 52597 Neighboring gene C1q-like 3 Neighboring gene STARR-seq mESC enhancer starr_03699 Neighboring gene STARR-positive B cell enhancer ABC_E5887 Neighboring gene STARR-positive B cell enhancer ABC_E1000 Neighboring gene STARR-positive B cell enhancer ABC_E5888 Neighboring gene STARR-seq mESC enhancer starr_03701 Neighboring gene STARR-seq mESC enhancer starr_03702 Neighboring gene predicted gene 13270 Neighboring gene cubilin Neighboring gene predicted gene, 57686

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    ras suppressor protein 1
    Names
    rsu-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001420897.1NP_001407826.1  ras suppressor protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL929209, AL935271
      UniProtKB/Swiss-Prot
      Q01730
    2. NM_001420898.1NP_001407827.1  ras suppressor protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL929209, AL935271
      UniProtKB/Swiss-Prot
      Q01730
      UniProtKB/TrEMBL
      A2AUR7
      Related
      ENSMUSP00000110439.3, ENSMUST00000114791.9
    3. NM_001420899.1NP_001407828.1  ras suppressor protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL935271
      UniProtKB/TrEMBL
      Q3TFN7
      Related
      ENSMUST00000162223.8
    4. NM_001420900.1NP_001407829.1  ras suppressor protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL929209, AL935271
      UniProtKB/Swiss-Prot
      Q01730
    5. NM_001420901.1NP_001407830.1  ras suppressor protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL929209, AL935271
    6. NM_001420902.1NP_001407831.1  ras suppressor protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL929209, AL935271
      UniProtKB/TrEMBL
      Q9CSE4
    7. NM_001420903.1NP_001407832.1  ras suppressor protein 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL935271
      UniProtKB/TrEMBL
      B1AYQ0
      Related
      ENSMUSP00000117460.2, ENSMUST00000137670.3
    8. NM_001420904.1NP_001407833.1  ras suppressor protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL928807, AL935271
    9. NM_001420905.1NP_001407834.1  ras suppressor protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL928807
    10. NM_009105.5NP_033131.2  ras suppressor protein 1 isoform 1

      See identical proteins and their annotated locations for NP_033131.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AL928807, AL929209, AL935271
      Consensus CDS
      CCDS15693.1
      UniProtKB/Swiss-Prot
      Q01730
      UniProtKB/TrEMBL
      Q9D031
      Related
      ENSMUSP00000028059.3, ENSMUST00000028059.9
      Conserved Domains (2) summary
      COG4886
      Location:38202
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:1941
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      13081778..13276116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)