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    Y71H2AM.1 N(6)-L-threonylcarbamoyladenine synthase [ Caenorhabditis elegans ]

    Gene ID: 175399, updated on 9-Dec-2024

    Summary

    Official Symbol
    Y71H2AM.1
    Official Full Name
    N(6)-L-threonylcarbamoyladenine synthase
    Primary source
    WormBase:WBGene00022166
    Locus tag
    CELE_Y71H2AM.1
    See related
    AllianceGenome:WB:WBGene00022166
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in nucleus. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 3. Orthologous to human OSGEP (O-sialoglycoprotein endopeptidase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Y71H2AM.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (2827070..2833037)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Elongation factor Tu, mitochondrial Neighboring gene Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Thioredoxin domain-containing protein 17 Neighboring gene ubiquitinyl hydrolase 1

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables N(6)-L-threonylcarbamoyladenine synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in tRNA modification IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA threonylcarbamoyladenosine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA threonylcarbamoyladenosine modification IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of EKC/KEOPS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N(6)-L-threonylcarbamoyladenine synthase
    NP_001370840.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2827070..2833037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001384044.2NP_001370840.1  N(6)-L-threonylcarbamoyladenine synthase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL28
      Conserved Domains (1) summary
      PTZ00340
      Location:4337
      PTZ00340; O-sialoglycoprotein endopeptidase-like protein; Provisional