U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    nhr-40 Nuclear hormone receptor family member nhr-40 [ Caenorhabditis elegans ]

    Gene ID: 180560, updated on 9-Dec-2024

    Summary

    Official Symbol
    nhr-40
    Official Full Name
    Nuclear hormone receptor family member nhr-40
    Primary source
    WormBase:WBGene00003630
    Locus tag
    CELE_T03G6.2
    See related
    AllianceGenome:WB:WBGene00003630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including P1; P10; P11; egg-laying apparatus; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See nhr-40 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (2594003..2606732)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene YitH/HolE acetyltransferase (GNAT) domain-containing protein Neighboring gene glycerophosphocholine cholinephosphodiesterase Neighboring gene tRNA-Gly

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding  
    enables DNA-binding transcription factor activity  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding  
    enables metal ion binding  
    enables nuclear receptor activity  
    enables sequence-specific DNA binding  
    enables zinc ion binding  
    Component Evidence Code Pubs
    located_in nucleus  

    General protein information

    Preferred Names
    Nuclear hormone receptor family member nhr-40
    NP_001024873.1
    • Confirmed by transcript evidence
    NP_001362027.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2594003..2606732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029702.5 → NP_001024873.1  Nuclear hormone receptor family member nhr-40 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024873.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22127
      Conserved Domains (2) summary
      cd06960
      Location:15 → 90
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:230 → 405
      HOLI; Ligand binding domain of hormone receptors
    2. NM_001374979.2 → NP_001362027.1  Nuclear hormone receptor family member nhr-40 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22127, Q8MPY4, Q9GTH6
      Conserved Domains (2) summary
      cd06960
      Location:31 → 106
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:246 → 421
      HOLI; Ligand binding domain of hormone receptors
    External link. Please review our privacy policy.