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    F53H1.4 PHD-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176944, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F53H1.4
    Official Full Name
    PHD-type domain-containing protein
    Primary source
    WormBase:WBGene00018778
    Locus tag
    CELE_F53H1.4
    See related
    AllianceGenome:WB:WBGene00018778
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Is expressed in gonad. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F53H1.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    15
    Sequence:
    Chromosome: IV; NC_003282.8 (1310166..1328243)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Calponin-homology (CH) domain-containing protein Neighboring gene ATP-dependent RNA helicase;Pre-mRNA-processing ATP-dependent RNA helicase PRP5;RNA helicase Neighboring gene UDENN domain-containing protein Neighboring gene pseudo Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    2. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PHD-type domain-containing protein
    NP_001023217.2
    • Confirmed by transcript evidence
    NP_001379979.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      1310166..1328243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028046.7 → NP_001023217.2  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023217.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45075
      Conserved Domains (2) summary
      smart00249
      Location:1044 → 1094
      PHD; PHD zinc finger
      pfam15613
      Location:748 → 853
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif

    2. NM_001392255.1 → NP_001379979.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86MG4
      Conserved Domains (1) summary
      smart00249
      Location:1008 → 1058
      PHD; PHD zinc finger
    Nucleotide Protein
    Heading Accession and Version

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