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    C49H3.4 Sm domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183627, updated on 9-Dec-2024

    Summary

    Official Symbol
    C49H3.4
    Official Full Name
    Sm domain-containing protein
    Primary source
    WormBase:WBGene00016791
    Locus tag
    CELE_C49H3.4
    See related
    AllianceGenome:WB:WBGene00016791
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable U7 snRNA binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Predicted to be part of U7 snRNP. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human LSM11 (LSM11, U7 small nuclear RNA associated). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See C49H3.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (7915291..7916710)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cortactin-binding protein-2 N-terminal domain-containing protein Neighboring gene C3HC-type domain-containing protein Neighboring gene CCR4-NOT transcription complex subunit 4 Neighboring gene Exportin-T Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables U7 snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables U7 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA 3'-end processing by stem-loop binding and cleavage IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of U7 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Sm domain-containing protein
    NP_001379819.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7915291..7916710
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392339.1NP_001379819.1  Sm domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GYQ8
      Conserved Domains (1) summary
      cl00259
      Location:120221
      Sm_like; Sm and related proteins