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    lnkn-1 Protein linkin [ Caenorhabditis elegans ]

    Gene ID: 176253, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lnkn-1
    Official Full Name
    Protein linkin
    Primary source
    WormBase:WBGene00014023
    Locus tag
    CELE_ZK637.3
    See related
    AllianceGenome:WB:WBGene00014023
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cell adhesion. Located in apical plasma membrane and lateral plasma membrane. Is expressed in several structures, including dorsal uterine precursor; excretory cell; gonad; hypodermis; and nervous system. Orthologous to human ITFG1 (integrin alpha FG-GAP repeat containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lnkn-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (8890231..8894213)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Putative transporter svop-1 Neighboring gene FAM161 homolog famh-136 Neighboring gene putative RING finger protein ZK637.14 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ATPase asna-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
    2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    3. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    4. LINKIN, a new transmembrane protein necessary for cell adhesion. Kato M, et al. Elife, 2014 Dec 1. PMID 25437307, Free PMC Article
    5. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in lateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein linkin
    NP_001369829.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8890231..8894213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001382950.2 → NP_001369829.1  Protein linkin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P30639
      Conserved Domains (1) summary
      pfam13517
      Location:36 → 106
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P30639.1

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