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    glb-13 Globin-related protein glb-13 [ Caenorhabditis elegans ]

    Gene ID: 184697, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glb-13
    Official Full Name
    Globin-related protein glb-13
    Primary source
    WormBase:WBGene00008957
    Locus tag
    CELE_F19H6.2
    See related
    AllianceGenome:WB:WBGene00008957
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Is expressed in head; somatic nervous system; and tail neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See glb-13 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (12374222..12378393, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene tRNA-Glu Neighboring gene BRCT domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Serine/threonine-protein kinase nekl-3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GLB-13 is associated with oxidative stress resistance in Caenorhabditis elegans. Ren C, et al. IUBMB Life, 2013 May. PMID 23508993
    2. The Caenorhabditis globin gene family reveals extensive nematode-specific radiation and diversification. Hoogewijs D, et al. BMC Evol Biol, 2008 Oct 9. PMID 18844991, Free PMC Article
    3. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
    4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. glb-13 is associated with the resistance against oxidative stress-induced toxicity.
      Title: GLB-13 is associated with oxidative stress resistance in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen carrier activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in oxygen transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Globin-related protein glb-13
    NP_510079.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12374222..12378393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077678.8 → NP_510079.2  Globin-related protein glb-13 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510079.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19601
      Conserved Domains (1) summary
      cd01040
      Location:109 → 244
      Mb-like; myoglobin-like; M family globin domain
    Nucleotide Protein
    Heading Accession and Version

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