cyn-10 Peptidyl-prolyl cis-trans isomerase 10 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cyn-10
Official Full Name: Peptidyl-prolyl cis-trans isomerase 10
Primary source: WormBase:WBGene00000886
Locus tag: CELE_B0252.4
See related: AllianceGenome:WB:WBGene00000886
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human PPIL3 (peptidylprolyl isomerase like 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cyn-10 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (6912540..6913365, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0252.4 (e-PCR)
- UniSTS:315300

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables peptidyl-prolyl cis-trans isomerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptidyl-prolyl cis-trans isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein peptidyl-prolyl isomerization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Peptidyl-prolyl cis-trans isomerase 10

NP_001021890.1

Confirmed by transcript evidence

NP_495416.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

6912540..6913365 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001026719.5 → NP_001021890.1 Peptidyl-prolyl cis-trans isomerase 10 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001021890.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P52017, Q95ZZ8

Conserved Domains (1) summary

cd01928
Location:1 → 153

Cyclophilin_PPIL3_like; Cyclophilin_PPIL3_like. Proteins similar to Human cyclophilin-like peptidylprolyl cis- trans isomerase (PPIL3). Members of this family lack a key residue important for cyclosporin binding: the tryptophan residue corresponding to W121 in human hCyP-18a; ...
NM_063015.5 → NP_495416.2 Peptidyl-prolyl cis-trans isomerase 10 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_495416.2

Status: REVIEWED

UniProtKB/Swiss-Prot

P52017

Conserved Domains (1) summary

cd01928
Location:1 → 147

Cyclophilin_PPIL3_like; Cyclophilin_PPIL3_like. Proteins similar to Human cyclophilin-like peptidylprolyl cis- trans isomerase (PPIL3). Members of this family lack a key residue important for cyclosporin binding: the tryptophan residue corresponding to W121 in human hCyP-18a; ...