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    plep-1 UNC93-like protein MFSD11 [ Caenorhabditis elegans ]

    Gene ID: 190188, updated on 9-Dec-2024

    Summary

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    Official Symbol
    plep-1
    Official Full Name
    UNC93-like protein MFSD11
    Primary source
    WormBase:WBGene00021797
    Locus tag
    CELE_Y52E8A.4
    See related
    AllianceGenome:WB:WBGene00021797
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Is expressed in excretory cell. Orthologous to human MFSD11 (major facilitator superfamily domain containing 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See plep-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (4309635..4312215, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Thioredoxin domain-containing protein Neighboring gene Transcription initiation factor IIF subunit alpha Neighboring gene protein-disulfide reductase Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reproductive Evolution: Pulling the Plug on Selection. Reilly DK, et al. Curr Biol, 2015 Oct 19. PMID 26485371
    2. Natural Variation in plep-1 Causes Male-Male Copulatory Behavior in C. elegans. Noble LM, et al. Curr Biol, 2015 Oct 19. PMID 26455306, Free PMC Article
    3. WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans. Snoek BL, et al. Database (Oxford), 2020 Jan 1. PMID 31960906, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UNC93-like protein MFSD11
    NP_001300605.1
    • Confirmed by transcript evidence
    NP_001300606.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4309635..4312215 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001313676.4 → NP_001300605.1  UNC93-like protein MFSD11 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AR66
      Conserved Domains (2) summary
      pfam05978
      Location:14 → 170
      UNC-93; Ion channel regulatory protein UNC-93
      pfam07690
      Location:54 → 388
      MFS_1; Major Facilitator Superfamily

    2. NM_001313677.3 → NP_001300606.1  UNC93-like protein MFSD11 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AUS1
      Conserved Domains (1) summary
      cl21472
      Location:1 → 73
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    Nucleotide Protein
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