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    Y105E8A.11 BolA-like protein 3 [ Caenorhabditis elegans ]

    Gene ID: 173306, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y105E8A.11
    Official Full Name
    BolA-like protein 3
    Primary source
    WormBase:WBGene00013671
    Locus tag
    CELE_Y105E8A.11
    See related
    AllianceGenome:WB:WBGene00013671
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein maturation by [4Fe-4S] cluster transfer. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 2. Orthologous to human BOLA3 (bolA family member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y105E8A.11 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (14432791..14433750)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene AP-1 complex subunit gamma Neighboring gene Non-lysosomal glucosylceramidase Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cation-transporting P-type ATPase N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein maturation by [4Fe-4S] cluster transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BolA-like protein 3
    NP_740939.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14432791..14433750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170943.9 → NP_740939.1  BolA-like protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_740939.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NEY7
      Conserved Domains (1) summary
      cl00386
      Location:30 → 105
      BolA; BolA-like protein
    Nucleotide Protein
    Heading Accession and Version

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