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    B0524.2 PNPLA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182024, updated on 9-Dec-2024

    Summary

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    Official Symbol
    B0524.2
    Official Full Name
    PNPLA domain-containing protein
    Primary source
    WormBase:WBGene00015241
    Locus tag
    CELE_B0524.2
    See related
    AllianceGenome:WB:WBGene00015241
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Predicted to be active in cytoplasm; lipid droplet; and membrane. Orthologous to human PNPLA4 (patatin like phospholipase domain containing 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See B0524.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (1894057..1899919)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene protein of unknown function WSN domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene HMG box domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Polyglutamine-repeat protein pqn-41 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables triacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retinol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in triglyceride catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PNPLA domain-containing protein
    NP_497474.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1894057..1899919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065073.5 → NP_497474.3  PNPLA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497474.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N5Z7
      Conserved Domains (1) summary
      cd07222
      Location:96 → 345
      Pat_PNPLA4; Patatin-like phospholipase domain containing protein 4
    Nucleotide Protein
    Heading Accession and Version

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