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    sel-7 Putative transcription factor sel-7 [ Caenorhabditis elegans ]

    Gene ID: 181539, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sel-7
    Official Full Name
    Putative transcription factor sel-7
    Primary source
    WormBase:WBGene00004764
    Locus tag
    CELE_K04G11.2
    See related
    AllianceGenome:WB:WBGene00004764
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables identical protein binding activity and sequence-specific DNA binding activity. Involved in several processes, including lateral inhibition; negative regulation of transcription by RNA polymerase II; and positive regulation of Notch signaling pathway. Located in nucleus. Is expressed in body wall musculature; pharyngeal muscle cell; and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sel-7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (14332738..14340481, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene RSD-2 N-terminal domain-containing protein Neighboring gene WD repeat-containing protein wdr-5.2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The temporally regulated transcription factor sel-7 controls developmental timing in C. elegans. Xia D, et al. Dev Biol, 2009 Aug 15. PMID 19500563
    2. sel-7, a positive regulator of lin-12 activity, encodes a novel nuclear protein in Caenorhabditis elegans. Chen J, et al. Genetics, 2004 Jan. PMID 15020414, Free PMC Article
    3. Identification and characterization of genes that interact with lin-12 in Caenorhabditis elegans. Tax FE, et al. Genetics, 1997 Dec. PMID 9409830, Free PMC Article
    4. New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme. Katic I, et al. Genetics, 2005 Dec. PMID 16157663, Free PMC Article
    5. miRNAs give worms the time of their lives: small RNAs and temporal control in Caenorhabditis elegans. Resnick TD, et al. Dev Dyn, 2010 May. PMID 20232378, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lateral inhibition IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of Notch signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of cell fate specification IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of development, heterochronic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of mesodermal cell fate specification IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative transcription factor sel-7
    NP_510392.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14332738..14340481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077991.7 → NP_510392.2  Putative transcription factor sel-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510392.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EGS7
    Nucleotide Protein
    Heading Accession and Version

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