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    phf-14 PHD-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180169, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phf-14
    Official Full Name
    PHD-type domain-containing protein
    Primary source
    WormBase:WBGene00013339
    Locus tag
    CELE_Y59A8A.2
    See related
    AllianceGenome:WB:WBGene00013339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human PHF14 (PHD finger protein 14). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See phf-14 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (17871393..17879916)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ribosome-binding protein 1 Neighboring gene COP9 signalosome complex subunit 1 Neighboring gene SAM-dependent methyltransferase Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Holin Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    2. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of MOZ/MORF histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PHD-type domain-containing protein
    NP_507508.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      17871393..17879916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075107.5 → NP_507508.2  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507508.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GRZ5
      Conserved Domains (2) summary
      cd15561
      Location:107 → 155
      PHD1_PHF14; PHD finger 1 found in PHD finger protein 14 (PHF14) and similar proteins
      cl22851
      Location:165 → 282
      PHD_SF; PHD finger superfamily
    Nucleotide Protein
    Heading Accession and Version

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