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    nstp-2 UDP-xylose and UDP-N-acetylglucosamine transporter [ Caenorhabditis elegans ]

    Gene ID: 177424, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nstp-2
    Official Full Name
    UDP-xylose and UDP-N-acetylglucosamine transporter
    Primary source
    WormBase:WBGene00017480
    Locus tag
    CELE_F15B10.1
    See related
    AllianceGenome:WB:WBGene00017480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Predicted to be involved in UDP-N-acetylglucosamine transmembrane transport. Predicted to be located in endomembrane system and membrane. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in hypodermis; intestine; nervous system; and pharynx. Orthologous to human SLC35B4 (solute carrier family 35 member B4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nstp-2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (6603998..6606188, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SUPpressor Neighboring gene ncRNA Neighboring gene BTB domain-containing protein Neighboring gene Helicase ATP-binding domain-containing protein;RNA helicase Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the soma. Trimmer KA, et al. Cell Rep, 2023 Jun 27. PMID 37227820, Free PMC Article
    2. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-N-acetylglucosamine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-xylose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in UDP-N-acetylglucosamine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in UDP-xylose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-xylose and UDP-N-acetylglucosamine transporter
    NP_001040936.1
    • Confirmed by transcript evidence
    NP_001370348.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      6603998..6606188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383108.2 → NP_001370348.1  UDP-xylose and UDP-N-acetylglucosamine transporter [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q336L5
      Conserved Domains (1) summary
      pfam08449
      Location:1 → 278
      UAA; UAA transporter family

    2. NM_001047471.8 → NP_001040936.1  UDP-xylose and UDP-N-acetylglucosamine transporter [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040936.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44166
      Conserved Domains (2) summary
      pfam08449
      Location:7 → 310
      UAA; UAA transporter family
      cl23754
      Location:91 → 304
      EamA; EamA-like transporter family
    Nucleotide Protein
    Heading Accession and Version

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