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    blos-7 BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177119, updated on 9-Dec-2024

    Summary

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    Official Symbol
    blos-7
    Official Full Name
    BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein
    Primary source
    WormBase:WBGene00021376
    Locus tag
    CELE_Y37E11B.3
    See related
    AllianceGenome:WB:WBGene00021376
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Orthologous to human BORCS6 (BLOC-1 related complex subunit 6). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See blos-7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (3580970..3582906, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene OToPetrin-Like;Otopetrin-1;Otopetrin-2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Enhancer of polycomb homolog 1-like Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene Transcription initiation factor TFIID subunit 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8. Niwa S, et al. Curr Biol, 2017 Sep 11. PMID 28823680, Free PMC Article
    2. A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes. Fazeli G, et al. Curr Biol, 2023 Feb 27. PMID 36652947, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in lysosome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of BORC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein
    NP_001368345.1
    • Confirmed by transcript evidence
    NP_500377.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3580970..3582906 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067976.5 → NP_500377.1  BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500377.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TYN4
      Conserved Domains (1) summary
      pfam10157
      Location:22 → 151
      DUF2365; Uncharacterized conserved protein (DUF2365)

    2. NM_001380153.1 → NP_001368345.1  BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PN06
      Conserved Domains (1) summary
      pfam10157
      Location:1 → 67
      BORCS6; BLOC-1-related complex sub-unit 6
    Nucleotide Protein
    Heading Accession and Version

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