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    ZK550.6 putative phytanoyl-CoA dioxygenase [ Caenorhabditis elegans ]

    Gene ID: 178503, updated on 9-Dec-2024

    Summary

    Official Symbol
    ZK550.6
    Official Full Name
    putative phytanoyl-CoA dioxygenase
    Primary source
    WormBase:WBGene00014000
    Locus tag
    CELE_ZK550.6
    See related
    AllianceGenome:WB:WBGene00014000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phytanoyl-CoA dioxygenase activity. Predicted to be involved in fatty acid alpha-oxidation. Is expressed in intestine. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; orofacial cleft; and peroxisomal disease. Orthologous to human PHYH (phytanoyl-CoA 2-hydroxylase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ZK550.6 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (17260307..17262485, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Peptidase M3A/M3B catalytic domain-containing protein Neighboring gene ncRNA Neighboring gene HTH TFE/IIEalpha-type domain-containing protein Neighboring gene phytanoyl-CoA dioxygenase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables L-ascorbic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phytanoyl-CoA dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phytanoyl-CoA dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in fatty acid alpha-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid alpha-oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    putative phytanoyl-CoA dioxygenase
    NP_503062.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17260307..17262485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070661.6NP_503062.1  putative phytanoyl-CoA dioxygenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503062.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O62515
      Conserved Domains (1) summary
      pfam05721
      Location:24244
      PhyH; Phytanoyl-CoA dioxygenase (PhyH)