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    col-80 Putative cuticle collagen 80 [ Caenorhabditis elegans ]

    Gene ID: 174652, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-80
    Official Full Name
    Putative cuticle collagen 80
    Primary source
    WormBase:WBGene00000656
    Locus tag
    CELE_C09G5.5
    See related
    AllianceGenome:WB:WBGene00000656
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human COL21A1 (collagen type XXI alpha 1 chain). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-80 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (10707201..10708287)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 Neighboring gene Putative cuticle collagen 79 Neighboring gene Cuticle collagen 39 Neighboring gene Cuticle collagen bli-1 Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Jackson J, et al. Mol Metab, 2022 Jul. PMID 35452878, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative cuticle collagen 80
    NP_496310.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10707201..10708287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063909.9 → NP_496310.1  Putative cuticle collagen 80 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496310.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09456
      Conserved Domains (1) summary
      smart01088
      Location:4 → 56
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09456.1

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