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    anmt-3 Nicotinamide N-methyltransferase-like [ Caenorhabditis elegans ]

    Gene ID: 179385, updated on 9-Dec-2024

    Summary

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    Official Symbol
    anmt-3
    Official Full Name
    Nicotinamide N-methyltransferase-like
    Primary source
    WormBase:WBGene00011573
    Locus tag
    CELE_T07C12.9
    See related
    AllianceGenome:WB:WBGene00011573
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable N-methyltransferase activity. Predicted to be involved in methylation. Predicted to be active in cytosol. Is expressed in body wall musculature and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm. Orthologous to human NNMT (nicotinamide N-methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See anmt-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (9956879..9958331, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene Transthyretin-like protein 46 Neighboring gene MAM domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The embryonic muscle transcriptome of Caenorhabditis elegans. Fox RM, et al. Genome Biol, 2007. PMID 17848203, Free PMC Article
    2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Nicotinamide N-methyltransferase-like
    NP_505563.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9956879..9958331 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073162.9 → NP_505563.1  Nicotinamide N-methyltransferase-like [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505563.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22279
      Conserved Domains (1) summary
      pfam01234
      Location:30 → 280
      NNMT_PNMT_TEMT; NNMT/PNMT/TEMT family
    Nucleotide Protein
    Heading Accession and Version

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