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    lgc-1 Neur_chan_LBD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 188099, updated on 9-Dec-2024

    Summary

    Official Symbol
    lgc-1
    Official Full Name
    Neur_chan_LBD domain-containing protein
    Primary source
    WormBase:WBGene00020236
    Locus tag
    CELE_T05B4.1
    See related
    AllianceGenome:WB:WBGene00020236
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in chemical synaptic transmission; monoatomic ion transmembrane transport; and regulation of membrane potential. Predicted to be located in membrane and postsynapse. Predicted to be part of transmembrane transporter complex. Predicted to be active in neuron projection; plasma membrane; and synapse. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See lgc-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (4135028..4138825)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ShKT domain-containing protein Neighboring gene Nuclear hormone receptor family member nhr-57 Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1 Neighboring gene Activin_recp domain-containing protein;Protein sleepless

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in chemical synaptic transmission  
    involved_in excitatory postsynaptic potential  
    involved_in monoatomic ion transmembrane transport  
    involved_in monoatomic ion transmembrane transport  
    involved_in monoatomic ion transport  
    involved_in regulation of membrane potential  
    involved_in regulation of postsynaptic membrane potential  
    Component Evidence Code Pubs
    located_in membrane  
    is_active_in neuron projection  
    is_active_in plasma membrane  
    located_in postsynapse  
    is_active_in synapse  
    part_of transmembrane transporter complex  

    General protein information

    Preferred Names
    Neur_chan_LBD domain-containing protein
    NP_504154.5
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4135028..4138825
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071753.7NP_504154.5  Neur_chan_LBD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16426
      Conserved Domains (1) summary
      cl27321
      Location:84335
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
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