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    tps-2 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2;Trehalose-6-phosphate phosphatase C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565050, updated on 9-Dec-2024

    Summary

    Official Symbol
    tps-2
    Official Full Name
    Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2;Trehalose-6-phosphate phosphatase C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00006603
    Locus tag
    CELE_F19H8.1
    See related
    AllianceGenome:WB:WBGene00006603
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity and trehalose-phosphatase activity. Predicted to be involved in trehalose biosynthetic process and trehalose metabolism in response to stress. Is expressed in body wall musculature; hypodermis; intestine; muscle cell; and reproductive system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See tps-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    14
    Sequence:
    Chromosome: II; NC_003280.10 (14600902..14610554)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Sodium/potassium-transporting ATPase subunit alpha Neighboring gene ShKT domain-containing protein Neighboring gene ncRNA Neighboring gene ADP-ribosylation factor-like protein 3 Neighboring gene MLt-TeN (mlt-10) related Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene MLt-TeN (mlt-10) related

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in trehalose biosynthetic process  
    involved_in trehalose biosynthetic process  
    involved_in trehalose metabolic process  
    involved_in trehalose metabolism in response to stress  

    General protein information

    Preferred Names
    Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2;Trehalose-6-phosphate phosphatase C-terminal domain-containing protein
    NP_001364816.1
    • Confirmed by transcript evidence
    NP_497035.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      14600902..14610554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064634.6 → NP_497035.3  Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497035.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45380, Q7YZT5
      Conserved Domains (3) summary
      cd03788
      Location:238 → 787
      GT1_TPS; Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a ...
      TIGR01484
      Location:934 → 1158
      HAD-SF-IIB; HAD-superfamily hydrolase, subfamily IIB
      TIGR02400
      Location:238 → 787
      trehalose_OtsA; alpha,alpha-trehalose-phosphate synthase [UDP-forming]
    2. NM_001377904.2 → NP_001364816.1  Trehalose-6-phosphate phosphatase C-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PLZ2
      Conserved Domains (1) summary
      cl21460
      Location:135 → 177
      HAD_like; Haloacid Dehalogenase-like Hydrolases
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