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    lir-2 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174239, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lir-2
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00003045
    Locus tag
    CELE_F18A1.4
    See related
    AllianceGenome:WB:WBGene00003045
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in developing hermaphrodite gonad; germ line; head ganglion; head neurons; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lir-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (7667267..7671909)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Chondroitin proteoglycan 4 domain-containing protein Neighboring gene putative replication factor A 73 kDa subunit Neighboring gene BED-type domain-containing protein;LIn-26 Related Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design. Farboud B, et al. Genetics, 2015 Apr. PMID 25695951, Free PMC Article
    2. lir-2, lir-1 and lin-26 encode a new class of zinc-finger proteins and are organized in two overlapping operons both in Caenorhabditis elegans and in Caenorhabditis briggsae. Dufourcq P, et al. Genetics, 1999 May. PMID 10224256, Free PMC Article
    3. RNA interference can target pre-mRNA: consequences for gene expression in a Caenorhabditis elegans operon. Bosher JM, et al. Genetics, 1999 Nov. PMID 10545456, Free PMC Article
    4. Multiple regulatory elements with spatially and temporally distinct activities control the expression of the epithelial differentiation gene lin-26 in C. elegans. Landmann F, et al. Dev Biol, 2004 Jan 15. PMID 14732406
    5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_001022098.1
    • Confirmed by transcript evidence
    NP_001379583.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7667267..7671909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393121.1 → NP_001379583.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9Y049

    2. NM_001026927.3 → NP_001022098.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022098.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGH3
    Nucleotide Protein
    Heading Accession and Version

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