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    T27E9.2 Cytochrome b-c1 complex subunit 6 [ Caenorhabditis elegans ]

    Gene ID: 176772, updated on 9-Dec-2024

    Summary

    Official Symbol
    T27E9.2
    Official Full Name
    Cytochrome b-c1 complex subunit 6
    Primary source
    WormBase:WBGene00012094
    Locus tag
    CELE_T27E9.2
    See related
    AllianceGenome:WB:WBGene00012094
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to human UQCRH (ubiquinol-cytochrome c reductase hinge protein) and UQCRHL (ubiquinol-cytochrome c reductase hinge protein like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See T27E9.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003281.10 (13462357..13462584, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene P-type Cu(+) transporter Neighboring gene ABC transporter domain-containing protein Neighboring gene Major sperm protein Neighboring gene ADP/ATP translocase Neighboring gene Cyclin-dependent-like kinase 5 Neighboring gene BTB domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex III IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Cytochrome b-c1 complex subunit 6
    NP_499781.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13462357..13462584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067380.6NP_499781.1  Cytochrome b-c1 complex subunit 6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499781.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45864
      Conserved Domains (1) summary
      pfam02320
      Location:1474
      UCR_hinge; Ubiquinol-cytochrome C reductase hinge protein