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    Btnl7 butyrophilin-like 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 406159, updated on 27-Nov-2024

    Summary

    Symbol
    Btnl7provided by RGD
    Full Name
    butyrophilin-like 7provided by RGD
    Primary source
    RGD:1303124
    See related
    EnsemblRapid:ENSRNOG00000000446 AllianceGenome:RGD:1303124
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 7.7), Spleen (RPKM 3.9) and 6 other tissues See more
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    Genomic context

    See Btnl7 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (4303002..4315445)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (4301078..4313522)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (2757008..2769215, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 21, subfamily a, polypeptide 1, pseudogene Neighboring gene butyrophilin-like 4 Neighboring gene butyrophilin-like 8 Neighboring gene butyrophilin-like 6, pseudogene 1 Neighboring gene butyrophilin-like 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    butyrophilin-like 7
    Names
    butyrophilin subfamily 1 member A1-like
    butyrophilin subfamily 3 member A3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395150.1NP_001382079.1  butyrophilin-like 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      D3ZL66, Q6MG93
      Related
      ENSRNOP00000098177.1, ENSRNOT00000120524.2
      Conserved Domains (3) summary
      cd13733
      Location:288441
      SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
      cd00096
      Location:4247
      Ig; Ig strand D [structural motif]
      cl11960
      Location:2990
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      4303002..4315445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279338.1XP_063135408.1  butyrophilin-like 7 isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_212488.1: Suppressed sequence

      Description
      NM_212488.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.