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    TENM3-AS1 TENM3 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 90768, updated on 26-Oct-2024

    Summary

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    Official Symbol
    TENM3-AS1provided by HGNC
    Official Full Name
    TENM3 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:28076
    See related
    AllianceGenome:HGNC:28076
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TENM3-AS2
    Expression
    Broad expression in placenta (RPKM 1.1), fat (RPKM 1.1) and 15 other tissues See more
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    Genomic context

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    See TENM3-AS1 in Genome Data Viewer
    Location:
    4q34.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (182138658..182144515, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (185480476..185486333, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (183059811..183065668, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene teneurin transmembrane protein 3 Neighboring gene RN7SK pseudogene 13 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr4:182870312-182870817 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:182870818-182871322 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:182871323-182871827 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:182930857-182931357 Neighboring gene cyclin H pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22175 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22176 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:183005741-183006264 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:183006265-183006786 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:183062164-183062970 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:183065925-183066913 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:183110451-183111650 Neighboring gene uncharacterized LOC105377572 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:183128595-183128794 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:183129869-183130370 Neighboring gene microRNA 1305

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Replication of top markers of a genome-wide association study in multiple sclerosis in Spain. Cavanillas ML, et al. Genes Immun, 2011 Mar. PMID 20944657
    2. Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. Zhao L, et al. Ann Hum Genet, 2013 Jul. PMID 23551011, Free PMC Article
    3. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Baranzini SE, et al. Hum Mol Genet, 2009 Feb 15. PMID 19010793, Free PMC Article
    4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Brandenberger R, et al. Nat Biotechnol, 2004 Jun. PMID 15146197
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. Oláh J, et al. J Biol Chem, 2011 Sep 30. PMID 21832049, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study of gene-disease association. (HuGE Navigator)
      Title: Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • TENM3 antisense transcript 2

    Clone Names

    • FLJ31634, FLJ36847, MGC45800, AC108142.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027107.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC108142, AI380807, AK024300, CN360795, DA736633

    2. NR_125905.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate segment, resulting in a shorter transcript compared to variant 1.
      Source sequence(s)
      AC108142, AI380807, CN360795, DA736567

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      182138658..182144515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      185480476..185486333 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials