Iglon5 IgLON family member 5 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Iglon5provided by MGI
Official Full Name: IgLON family member 5provided by MGI
Primary source: MGI:MGI:2686277
See related: Ensembl:ENSMUSG00000013367 AllianceGenome:MGI:2686277
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1431; A230106M20Rik
Summary: Predicted to be located in extracellular region. Is expressed in central nervous system; peripheral nervous system ganglion; and sensory organ. Orthologous to human IGLON5 (IgLON family member 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in whole brain E14.5 (RPKM 27.1), CNS E14 (RPKM 23.2) and 14 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B3; 7 28.25 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (43122325..43139635, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (43472901..43490211, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypic Insights Into Anti-IgLON5 Disease in IgLON5-Deficient Mice.
Title: Phenotypic Insights Into Anti-IgLON5 Disease in IgLON5-Deficient Mice.
IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
Title: IgLON5 deficiency produces behavioral alterations in a knockout mouse model.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (4)

General gene information

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Markers

D7Dcr12 (e-PCR), detects polymorphism
- UniSTS:507768

NoName (e-PCR)
- UniSTS:488352

D7Mit157 (e-PCR), detects polymorphism
- UniSTS:131052

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: igLON family member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001164518.2 → NP_001157990.1 igLON family member 5 precursor

See identical proteins and their annotated locations for NP_001157990.1

Status: VALIDATED

Source sequence(s)

AC154108

Consensus CDS

CCDS52223.1

UniProtKB/Swiss-Prot

A7E1X9, Q8HW98

Related

ENSMUSP00000103608.2, ENSMUST00000107974.3

Conserved Domains (3) summary

pfam13927
Location:217 → 295

Ig_3; Immunoglobulin domain

cd00096
Location:41 → 46

Ig; Ig strand A' [structural motif]

cl11960
Location:41 → 129

Ig; Immunoglobulin domain