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    Ino80b INO80 complex subunit B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500225, updated on 9-Dec-2024

    Summary

    Symbol
    Ino80bprovided by RGD
    Full Name
    INO80 complex subunit Bprovided by RGD
    Primary source
    RGD:1562258
    See related
    EnsemblRapid:ENSRNOG00000008873 AllianceGenome:RGD:1562258
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znhit4; RGD1562258
    Summary
    Predicted to be involved in several processes, including regulation of embryonic development; regulation of nucleobase-containing compound metabolic process; and telomere maintenance. Predicted to be located in nuclear body and nucleolus. Predicted to be part of Ino80 complex. Orthologous to human INO80B (INO80 complex subunit B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 101.4), Kidney (RPKM 88.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ino80b in Genome Data Viewer
    Location:
    4q34
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (117185427..117188930, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (115627907..115631069, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (113954612..113957774, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene mannosyl-oligosaccharide glucosidase Neighboring gene WW domain binding protein 1 Neighboring gene uncharacterized LOC108350719 Neighboring gene rhotekin Neighboring gene WD repeat domain 54 Neighboring gene similar to human chromosome 2 open reading frame 81

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of telomere maintenance in response to DNA damage ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA strand elongation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of chromosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in telomere maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Ino80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Ino80 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    INO80 complex subunit B
    Names
    PAP-1 binding protein
    high mobility group AT-hook 1-like 4
    zinc finger, HIT type 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048233.1NP_001041698.1  INO80 complex subunit B

      See identical proteins and their annotated locations for NP_001041698.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105625
      UniProtKB/TrEMBL
      Q0D2L4
      Related
      ENSRNOP00000011921.4, ENSRNOT00000011921.8
      Conserved Domains (2) summary
      pfam04438
      Location:307338
      zf-HIT; HIT zinc finger
      pfam04795
      Location:211291
      PAPA-1; PAPA-1-like conserved region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      117185427..117188930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286523.1XP_063142593.1  INO80 complex subunit B isoform X1