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    Wdr90 WD repeat domain 90 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102555298, updated on 3-Dec-2024

    Summary

    Official Symbol
    Wdr90provided by RGD
    Official Full Name
    WD repeat domain 90provided by RGD
    Primary source
    RGD:7520481
    See related
    EnsemblRapid:ENSRNOG00000020006 AllianceGenome:RGD:7520481
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561785
    Summary
    Predicted to be involved in cilium assembly. Predicted to be located in centrosome. Predicted to be active in centriole. Orthologous to human WDR90 (WD repeat domain 90). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 47.6), Thymus (RPKM 38.2) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Wdr90 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15369184..15385797, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14864672..14881285, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15211660..15229477, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene jumonji domain containing 8 Neighboring gene STIP1 homology and U-box containing protein 1 Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2 Neighboring gene MAPK regulated co-repressor interacting protein 2 Neighboring gene methyltransferase like 26 Neighboring gene transfer RNA glycine (anticodon CCC) 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    WD repeat domain 90; WD repeat-containing protein 90
    Names
    WD repeat-containing protein 90-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433408.1NP_001420337.1  WD repeat domain 90

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I5ZMK6, D3ZMM2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15369184..15385797 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246068.4XP_006246130.1  WD repeat-containing protein 90 isoform X2

      Related
      ENSRNOT00000027121.8
      Conserved Domains (4) summary
      COG2319
      Location:12561679
      WD40; WD40 repeat [General function prediction only]
      pfam05018
      Location:60236
      DUF667; Protein of unknown function (DUF667)
      sd00039
      Location:12851327
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:7581058
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_006246066.4XP_006246128.1  WD repeat-containing protein 90 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMK6
      Conserved Domains (4) summary
      COG2319
      Location:12561679
      WD40; WD40 repeat [General function prediction only]
      pfam05018
      Location:60236
      DUF667; Protein of unknown function (DUF667)
      sd00039
      Location:12851327
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:7581058
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. XM_039087116.1XP_038943044.1  WD repeat-containing protein 90 isoform X3

      Conserved Domains (3) summary
      COG2319
      Location:7321155
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:761803
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:234534
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. XM_063270092.1XP_063126162.1  WD repeat-containing protein 90 isoform X4