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    Metrn meteorin, glial cell differentiation regulator [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287151, updated on 27-Nov-2024

    Summary

    Official Symbol
    Metrnprovided by RGD
    Official Full Name
    meteorin, glial cell differentiation regulatorprovided by RGD
    Primary source
    RGD:1306222
    See related
    AllianceGenome:RGD:1306222
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hyrac; RGD1306222
    Summary
    Predicted to enable hormone activity. Predicted to be involved in glial cell differentiation and positive regulation of axonogenesis. Predicted to act upstream of or within radial glial cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human METRN (meteorin, glial cell differentiation regulator). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 234.1), Kidney (RPKM 164.3) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Metrn in Genome Data Viewer
    Location:
    10q12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15321200..15323218, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14816684..14818702, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15164439..15166457, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene hydroxyacylglutathione hydrolase-like Neighboring gene coiled-coil domain containing 78 Neighboring gene adenine nucleotide translocase lysine methyltransferase Neighboring gene F-box and leucine-rich repeat protein 16 Neighboring gene WD repeat domain 24

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hormone activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of axonogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glial cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of axonogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within radial glial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    meteorin
    Names
    hypoxia/reoxygenation regulatory factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009962.1NP_001009962.1  meteorin precursor

      See identical proteins and their annotated locations for NP_001009962.1

      Status: PROVISIONAL

      Source sequence(s)
      AY800384
      UniProtKB/Swiss-Prot
      Q5Q0T9
      UniProtKB/TrEMBL
      A0A8I6GLV8, A6HD55

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15321200..15323218 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)