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    Cdhr4 cadherin-related family member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363144, updated on 3-Dec-2024

    Summary

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    Symbol
    Cdhr4provided by RGD
    Full Name
    cadherin-related family member 4provided by RGD
    Primary source
    RGD:1306603
    See related
    EnsemblRapid:ENSRNOG00000061650 AllianceGenome:RGD:1306603
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cdh29; RGD1306603
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Orthologous to human CDHR4 (cadherin related family member 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 49.9), Testes (RPKM 30.2) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cdhr4 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (117561206..117594456)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (108682594..108690358)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (116771377..116779242)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-like modifier activating enzyme 7 Neighboring gene inka box actin regulator 1 Neighboring gene uncharacterized LOC134480233 Neighboring gene inositol hexakisphosphate kinase 1 Neighboring gene GDP-mannose pyrophosphorylase B Neighboring gene ring finger protein 123 Neighboring gene adhesion molecule with Ig like domain 3 Neighboring gene macrophage stimulating 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • AC128059.5

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cadherin-related family member 4
    Names
    cadherin-like 29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433382.1 → NP_001420311.1  cadherin-related family member 4 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JUE2

    2. NM_001433383.1 → NP_001420312.1  cadherin-related family member 4 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    3. NM_001433384.1 → NP_001420313.1  cadherin-related family member 4 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      117561206..117594456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266458.1 → XP_063122528.1  cadherin-related family member 4 isoform X6

    2. XM_063266460.1 → XP_063122530.1  cadherin-related family member 4 isoform X9

    3. XM_063266461.1 → XP_063122531.1  cadherin-related family member 4 isoform X13

      UniProtKB/TrEMBL
      A6I322

    4. XM_039082828.2 → XP_038938756.1  cadherin-related family member 4 isoform X1

      Conserved Domains (1) summary
      cd11304
      Location:464 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    5. XM_039082830.2 → XP_038938758.1  cadherin-related family member 4 isoform X4

      Conserved Domains (1) summary
      cd11304
      Location:464 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    6. XM_039082832.2 → XP_038938760.1  cadherin-related family member 4 isoform X8

      Conserved Domains (1) summary
      cd11304
      Location:464 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    7. XM_039082831.2 → XP_038938759.1  cadherin-related family member 4 isoform X7

      Conserved Domains (1) summary
      cd11304
      Location:464 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    8. XM_039082835.2 → XP_038938763.1  cadherin-related family member 4 isoform X12

      Conserved Domains (1) summary
      cd11304
      Location:464 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    9. XM_039082834.2 → XP_038938762.1  cadherin-related family member 4 isoform X11

      UniProtKB/TrEMBL
      A6I322
      Conserved Domains (1) summary
      cd11304
      Location:464 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    10. XM_039082836.2 → XP_038938764.1  cadherin-related family member 4 isoform X15

      UniProtKB/TrEMBL
      A6I322
      Conserved Domains (1) summary
      cd11304
      Location:464 → 556
      Cadherin_repeat; Cadherin tandem repeat domain

    11. XM_063266463.1 → XP_063122533.1  cadherin-related family member 4 isoform X16

      UniProtKB/TrEMBL
      A6I322

    12. XM_039082833.2 → XP_038938761.1  cadherin-related family member 4 isoform X10

      Conserved Domains (1) summary
      cd11304
      Location:464 → 535
      Cadherin_repeat; Cadherin tandem repeat domain

    13. XM_006243871.5 → XP_006243933.1  cadherin-related family member 4 isoform X2

      Conserved Domains (1) summary
      cd11304
      Location:447 → 544
      Cadherin_repeat; Cadherin tandem repeat domain

    14. XM_006243872.4 → XP_006243934.1  cadherin-related family member 4 isoform X5

      Related
      ENSRNOP00000106202.1, ENSRNOT00000137775.1
      Conserved Domains (1) summary
      cd11304
      Location:447 → 544
      Cadherin_repeat; Cadherin tandem repeat domain

    15. XM_063266462.1 → XP_063122532.1  cadherin-related family member 4 isoform X14

      UniProtKB/TrEMBL
      A6I322
      Related
      ENSRNOP00000069064.3, ENSRNOT00000083240.3

    16. XM_039082829.2 → XP_038938757.1  cadherin-related family member 4 isoform X3

      Conserved Domains (1) summary
      cd11304
      Location:446 → 543
      Cadherin_repeat; Cadherin tandem repeat domain

    17. XM_039082837.2 → XP_038938765.1  cadherin-related family member 4 isoform X17

      UniProtKB/TrEMBL
      A6I322
      Conserved Domains (1) summary
      cd11304
      Location:464 → 558
      Cadherin_repeat; Cadherin tandem repeat domain

    18. XM_039082839.2 → XP_038938767.1  cadherin-related family member 4 isoform X19

      Conserved Domains (1) summary
      cd11304
      Location:240 → 330
      Cadherin_repeat; Cadherin tandem repeat domain

    19. XM_039082838.2 → XP_038938766.1  cadherin-related family member 4 isoform X18

      Conserved Domains (1) summary
      cd11304
      Location:183 → 280
      Cadherin_repeat; Cadherin tandem repeat domain

    RNA

    1. XR_005488679.2 RNA Sequence

    2. XR_005488680.2 RNA Sequence

    3. XR_005488681.2 RNA Sequence

    4. XR_005488683.2 RNA Sequence

    5. XR_005488682.2 RNA Sequence

    6. XR_005488684.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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