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    Sstr5 somatostatin receptor 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25354, updated on 27-Nov-2024

    Summary

    Official Symbol
    Sstr5provided by RGD
    Official Full Name
    somatostatin receptor 5provided by RGD
    Primary source
    RGD:3765
    See related
    EnsemblRapid:ENSRNOG00000018834 AllianceGenome:RGD:3765
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Smstr5; Somato
    Summary
    Enables somatostatin receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and cellular response to glucocorticoid stimulus. Predicted to be active in neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in bipolar disorder. Orthologous to human SSTR5 (somatostatin receptor 5). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See Sstr5 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15010209..15017469, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14506868..14512946, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (14847749..14853827, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547952 Neighboring gene tektin 4 Neighboring gene uncharacterized LOC120095051 Neighboring gene SRY-box transcription factor 8

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables neuropeptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables somatostatin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables somatostatin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables somatostatin receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    somatostatin receptor type 5
    Names
    SS-5-R
    SS5-R
    SS5R
    Somatostatin receptor subtype 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430079.1NP_001417008.1  somatostatin receptor type 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HD30, G3V8G3
    2. NM_012882.3NP_037014.2  somatostatin receptor type 5

      See identical proteins and their annotated locations for NP_037014.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      P30938
      UniProtKB/TrEMBL
      A6HD30, G3V8G3
      Related
      ENSRNOP00000025451.1, ENSRNOT00000025451.4
      Conserved Domains (2) summary
      pfam00001
      Location:54303
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:48227
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15010209..15017469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268457.1XP_063124527.1  somatostatin receptor type 5 isoform X1

      Related
      ENSRNOP00000109656.1, ENSRNOT00000133850.1