U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DCDC1 doublecortin domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 341019, updated on 10-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DCDC1provided by HGNC
    Official Full Name
    doublecortin domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:20625
    See related
    Ensembl:ENSG00000170959 MIM:608062; AllianceGenome:HGNC:20625
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DCDC5
    Summary
    This gene encodes a member of the doublecortin family. The protein encoded by this gene is a hydrophilic, intracellular protein. It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization. This gene is mainly expressed in adult testis. It does not have a mouse homolog. [provided by RefSeq, Sep 2010]
    Expression
    Biased expression in testis (RPKM 2.0), thyroid (RPKM 0.3) and 3 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DCDC1 in Genome Data Viewer
    Location:
    11p14.1-p13
    Exon count:
    51
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (30863603..31369739, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (30997893..31505576, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (30885150..31391286, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928338 Neighboring gene long intergenic non-protein coding RNA 2859 Neighboring gene uncharacterized LOC107984419 Neighboring gene uncharacterized LOC124902656 Neighboring gene uncharacterized LOC105376611 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:30992221-30992721 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3218 Neighboring gene NANOG hESC enhancer GRCh37_chr11:31145398-31145899 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:31326823-31328022 Neighboring gene CYCS pseudogene 25 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4556 Neighboring gene MPRA-validated peak1237 silencer Neighboring gene MPRA-validated peak1238 silencer Neighboring gene DnaJ heat shock protein family (Hsp40) member C24 Neighboring gene MPRA-validated peak1240 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:31531307-31532196 Neighboring gene inner mitochondrial membrane peptidase subunit 1 Neighboring gene HCNE8 enhancer downstream of PAX6 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:31565420-31566029 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:31566030-31566638 Neighboring gene RB enhancer downstream of PAX6 Neighboring gene elongator acetyltransferase complex subunit 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4558 Neighboring gene E100 enhancer downstream of PAX6 Neighboring gene PAX6 downstream regulatory region Neighboring gene E60 enhancer downstream of PAX6 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:31800787-31801986 Neighboring gene paired box 6

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of a novel human doublecortin-domain-containing gene (DCDC1) expressed mainly in testis. Zeng L, et al. J Hum Genet, 2003. PMID 12820024
    2. A 556 kb deletion in the downstream region of the PAX6 gene causes familial aniridia and other eye anomalies in a Chinese family. Cheng F, et al. Mol Vis, 2011 Feb 10. PMID 21321669, Free PMC Article
    3. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. Meyer TE, et al. PLoS Genet, 2010 Aug 5. PMID 20700443, Free PMC Article
    4. Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein. Kaplan A, et al. J Cell Sci, 2011 Dec 1. PMID 22159412
    5. The doublecortin gene family and disorders of neuronal structure. Dijkmans TF, et al. Cent Nerv Syst Agents Med Chem, 2010 Mar. PMID 20236041

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator)
      Title: Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    3. DCDC5 colocalizes with Rab8 and links it to dynein during cytokinesis. DCDC5 knockdown increased apoptosis and the number of multinucleated cells.
      Title: Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein.
    4. DCDC1 was mapped to 11p13; mainly expressed in adult testis; and its expression in fetal brain was much higher than in adult brain
      Title: Identification of a novel human doublecortin-domain-containing gene (DCDC1) expressed mainly in testis.
    Submit: New GeneRIF Correction

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • FLJ44078, FLJ46154, KIAA1493, MGC190499, MGC190811, DKFZp779D068

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Flemming body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in midbody IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    doublecortin domain-containing protein 1
    Names
    doublecortin domain-containing 5 protein
    doublecortin domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001367979.1 → NP_001354908.1  doublecortin domain-containing protein 1 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AL133376, AL135932, AL137160, AL137804, AL162614
      Consensus CDS
      CCDS91454.1
      UniProtKB/Swiss-Prot
      A6PVL6, B1AL47, B7WNX6, M0R2J8, P59894, Q6ZRR9, Q6ZU04
      Related
      ENSP00000472625.1, ENST00000597505.5

    2. NM_001387274.1 → NP_001374203.1  doublecortin domain-containing protein 1 isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) encodes the longest isoform (6).
      Source sequence(s)
      AL133376, AL135932, AL137160, AL137804, AL162614
      Consensus CDS
      CCDS91453.1
      UniProtKB/TrEMBL
      A0A804HJA9
      Related
      ENSP00000507427.1, ENST00000684477.1
      Conserved Domains (7) summary
      cd00161
      Location:1163 → 1263
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cd17155
      Location:174 → 245
      DCX_DCDC1; Doublecortin-like domain found in doublecortin domain-containing protein 1 (DCDC1)
      cd17156
      Location:936 → 1013
      DCX1_DCDC5; Doublecortin-like domain 1 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17157
      Location:295 → 380
      DCX2_DCDC5; Doublecortin-like domain 2 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17158
      Location:1412 → 1552
      DCX3_DCDC5; Doublecortin-like domain 3 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17159
      Location:1670 → 1742
      DCX4_DCDC5; Doublecortin-like domain 4 found in doublecortin domain-containing protein 5 (DCDC5)
      cl28922
      Location:547 → 580
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    3. NM_001387275.1 → NP_001374204.1  doublecortin domain-containing protein 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AL133349, AL135932
      UniProtKB/TrEMBL
      H7C298
      Conserved Domains (3) summary
      cd00161
      Location:81 → 181
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cd17158
      Location:330 → 467
      DCX3_DCDC5; Doublecortin-like domain 3 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17159
      Location:585 → 657
      DCX4_DCDC5; Doublecortin-like domain 4 found in doublecortin domain-containing protein 5 (DCDC5)

    4. NM_020869.4 → NP_065920.2  doublecortin domain-containing protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AL133349, AL135932
      Consensus CDS
      CCDS73270.1
      UniProtKB/TrEMBL
      B6ZDN3, H7C298
      Related
      ENSP00000385936.3, ENST00000406071.6
      Conserved Domains (2) summary
      cd00161
      Location:270 → 370
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cl00155
      Location:514 → 576
      UBQ; Ubiquitin-like proteins

    5. NM_181807.4 → NP_861523.2  doublecortin domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_861523.2

      Status: REVIEWED

      Source sequence(s)
      AA846321, AA954541, AY247970
      Consensus CDS
      CCDS7872.1
      UniProtKB/Swiss-Prot
      P59894
      Related
      ENSP00000389792.1, ENST00000452803.1
      Conserved Domains (1) summary
      cl00155
      Location:170 → 252
      UBQ; Ubiquitin-like proteins

    RNA

    1. NR_170625.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL133376, AL135932, AL137160, AL137804, AL162614

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      30863603..31369739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024448478.2 → XP_024304246.1  doublecortin domain-containing protein 1 isoform X12

      Conserved Domains (6) summary
      cd00161
      Location:1063 → 1163
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cd17155
      Location:174 → 245
      DCX_DCDC1; Doublecortin-like domain found in doublecortin domain-containing protein 1 (DCDC1)
      cd17156
      Location:836 → 913
      DCX1_DCDC5; Doublecortin-like domain 1 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17158
      Location:1312 → 1452
      DCX3_DCDC5; Doublecortin-like domain 3 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17159
      Location:1570 → 1642
      DCX4_DCDC5; Doublecortin-like domain 4 found in doublecortin domain-containing protein 5 (DCDC5)
      cl28922
      Location:447 → 480
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_024448476.2 → XP_024304244.1  doublecortin domain-containing protein 1 isoform X10

      Conserved Domains (2) summary
      cd00161
      Location:1118 → 1218
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cl25424
      Location:1362 → 1424
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    3. XM_024448475.2 → XP_024304243.1  doublecortin domain-containing protein 1 isoform X9

      Conserved Domains (2) summary
      cd00161
      Location:1145 → 1245
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cl25424
      Location:1389 → 1451
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    4. XM_024448477.2 → XP_024304245.1  doublecortin domain-containing protein 1 isoform X11

      Conserved Domains (2) summary
      cd00161
      Location:1163 → 1263
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cl25424
      Location:932 → 1014
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    5. XM_024448473.2 → XP_024304241.1  doublecortin domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A804HJA9
      Conserved Domains (7) summary
      cd00161
      Location:1163 → 1263
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cd17155
      Location:174 → 245
      DCX_DCDC1; Doublecortin-like domain found in doublecortin domain-containing protein 1 (DCDC1)
      cd17156
      Location:936 → 1013
      DCX1_DCDC5; Doublecortin-like domain 1 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17157
      Location:295 → 380
      DCX2_DCDC5; Doublecortin-like domain 2 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17158
      Location:1412 → 1552
      DCX3_DCDC5; Doublecortin-like domain 3 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17159
      Location:1670 → 1742
      DCX4_DCDC5; Doublecortin-like domain 4 found in doublecortin domain-containing protein 5 (DCDC5)
      cl28922
      Location:547 → 580
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    6. XM_024448471.2 → XP_024304239.1  doublecortin domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A804HJA9
      Conserved Domains (7) summary
      cd00161
      Location:1163 → 1263
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cd17155
      Location:174 → 245
      DCX_DCDC1; Doublecortin-like domain found in doublecortin domain-containing protein 1 (DCDC1)
      cd17156
      Location:936 → 1013
      DCX1_DCDC5; Doublecortin-like domain 1 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17157
      Location:295 → 380
      DCX2_DCDC5; Doublecortin-like domain 2 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17158
      Location:1412 → 1552
      DCX3_DCDC5; Doublecortin-like domain 3 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17159
      Location:1670 → 1742
      DCX4_DCDC5; Doublecortin-like domain 4 found in doublecortin domain-containing protein 5 (DCDC5)
      cl28922
      Location:547 → 580
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    7. XM_024448480.2 → XP_024304248.1  doublecortin domain-containing protein 1 isoform X13

      Conserved Domains (2) summary
      cd00161
      Location:878 → 978
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cl25424
      Location:1122 → 1184
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    8. XM_024448481.2 → XP_024304249.1  doublecortin domain-containing protein 1 isoform X14

      Conserved Domains (2) summary
      cd00161
      Location:835 → 935
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cl25424
      Location:1079 → 1141
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    9. XM_024448472.2 → XP_024304240.1  doublecortin domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A804HJA9
      Conserved Domains (7) summary
      cd00161
      Location:1163 → 1263
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      cd17155
      Location:174 → 245
      DCX_DCDC1; Doublecortin-like domain found in doublecortin domain-containing protein 1 (DCDC1)
      cd17156
      Location:936 → 1013
      DCX1_DCDC5; Doublecortin-like domain 1 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17157
      Location:295 → 380
      DCX2_DCDC5; Doublecortin-like domain 2 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17158
      Location:1412 → 1552
      DCX3_DCDC5; Doublecortin-like domain 3 found in doublecortin domain-containing protein 5 (DCDC5)
      cd17159
      Location:1670 → 1742
      DCX4_DCDC5; Doublecortin-like domain 4 found in doublecortin domain-containing protein 5 (DCDC5)
      cl28922
      Location:547 → 580
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    10. XM_047426876.1 → XP_047282832.1  doublecortin domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A804HJA9

    11. XM_024448482.2 → XP_024304250.1  doublecortin domain-containing protein 1 isoform X15

      Conserved Domains (1) summary
      cl25424
      Location:932 → 1014
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    12. XM_024448484.2 → XP_024304252.1  doublecortin domain-containing protein 1 isoform X2

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    13. XM_024448483.2 → XP_024304251.1  doublecortin domain-containing protein 1 isoform X1

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    14. XM_024448485.2 → XP_024304253.1  doublecortin domain-containing protein 1 isoform X3

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    15. XM_024448486.2 → XP_024304254.1  doublecortin domain-containing protein 1 isoform X4

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    16. XM_024448487.2 → XP_024304255.1  doublecortin domain-containing protein 1 isoform X5

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    17. XM_024448488.2 → XP_024304256.1  doublecortin domain-containing protein 1 isoform X6

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    18. XM_024448489.2 → XP_024304257.1  doublecortin domain-containing protein 1 isoform X7

      Conserved Domains (1) summary
      cl25424
      Location:170 → 252
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

    RNA

    1. XR_002957144.2 RNA Sequence

    2. XR_002957145.2 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      30997893..31505576 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054368642.1 → XP_054224617.1  doublecortin domain-containing protein 1 isoform X22

    2. XM_054368640.1 → XP_054224615.1  doublecortin domain-containing protein 1 isoform X20

    3. XM_054368637.1 → XP_054224612.1  doublecortin domain-containing protein 1 isoform X17

    4. XM_054368639.1 → XP_054224614.1  doublecortin domain-containing protein 1 isoform X19

    5. XM_054368641.1 → XP_054224616.1  doublecortin domain-containing protein 1 isoform X21

    6. XM_054368638.1 → XP_054224613.1  doublecortin domain-containing protein 1 isoform X18

    7. XM_054368632.1 → XP_054224607.1  doublecortin domain-containing protein 1 isoform X16

    8. XM_054368636.1 → XP_054224611.1  doublecortin domain-containing protein 1 isoform X16

    9. XM_054368635.1 → XP_054224610.1  doublecortin domain-containing protein 1 isoform X16

    10. XM_054368644.1 → XP_054224619.1  doublecortin domain-containing protein 1 isoform X24

    11. XM_054368643.1 → XP_054224618.1  doublecortin domain-containing protein 1 isoform X23

    12. XM_054368645.1 → XP_054224620.1  doublecortin domain-containing protein 1 isoform X25

    13. XM_054368634.1 → XP_054224609.1  doublecortin domain-containing protein 1 isoform X16

    14. XM_054368633.1 → XP_054224608.1  doublecortin domain-containing protein 1 isoform X16

    15. XM_054368646.1 → XP_054224621.1  doublecortin domain-containing protein 1 isoform X26

    16. XM_054368648.1 → XP_054224623.1  doublecortin domain-containing protein 1 isoform X2

    17. XM_054368647.1 → XP_054224622.1  doublecortin domain-containing protein 1 isoform X1

    18. XM_054368649.1 → XP_054224624.1  doublecortin domain-containing protein 1 isoform X3

    19. XM_054368650.1 → XP_054224625.1  doublecortin domain-containing protein 1 isoform X4

    20. XM_054368651.1 → XP_054224626.1  doublecortin domain-containing protein 1 isoform X5

    21. XM_054368652.1 → XP_054224627.1  doublecortin domain-containing protein 1 isoform X6

    22. XM_054368653.1 → XP_054224628.1  doublecortin domain-containing protein 1 isoform X7

    RNA

    1. XR_008488391.1 RNA Sequence

    2. XR_008488392.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001350255.1: Suppressed sequence

      Description
      NM_001350255.1: This RefSeq was removed because currently there is insufficient support for the transcript and protein.

    2. NM_198462.2: Suppressed sequence

      Description
      NM_198462.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M0R2J8.1 GenPept UniProtKB/Swiss-Prot:M0R2J8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools