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    Krtap19-4 keratin associated protein 19-4 [ Mus musculus (house mouse) ]

    Gene ID: 170654, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Krtap19-4provided by MGI
    Official Full Name
    keratin associated protein 19-4provided by MGI
    Primary source
    MGI:MGI:2157757
    See related
    Ensembl:ENSMUSG00000043982 AllianceGenome:MGI:2157757
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Krtap16-4
    Summary
    Predicted to be located in intermediate filament. Orthologous to human KRTAP19-1 (keratin associated protein 19-1) and KRTAP19-3 (keratin associated protein 19-3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Krtap19-4 in Genome Data Viewer
    Location:
    16 C3.3; 16 51.42 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (88681660..88681977, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (88884786..88885089, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene keratin associated protein 19-2 Neighboring gene keratin associated protein 19-3 Neighboring gene keratin associated protein 19-5 Neighboring gene keratin associated protein 19-9B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia. Tkatchenko AV, et al. Development, 2001 May. PMID 11290294
    2. Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13. Pruett ND, et al. J Biol Chem, 2004 Dec 3. PMID 15385554
    3. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair. Wu DD, et al. BMC Evol Biol, 2008 Aug 23. PMID 18721477, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Krtap16 is a hair keratin-associated protein gene complex regulated by Hoxc13; localized to chromosome 16
      Title: Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    keratin-associated protein 19-4
    Names
    keratin-associated protein 16-4
    keratin-associated protein 16.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130873.1 → NP_570943.1  keratin-associated protein 19-4

      Status: PROVISIONAL

      Source sequence(s)
      AF345294
      Consensus CDS
      CCDS37387.1
      UniProtKB/Swiss-Prot
      Q925H7
      Related
      ENSMUSP00000056250.3, ENSMUST00000051103.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      88681660..88681977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159806.1 → XP_036015699.1  keratin-associated protein 19-4 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q925H7.1 GenPept UniProtKB/Swiss-Prot:Q925H7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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