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    MRP7 mitochondrial 54S ribosomal protein YmL2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855727, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRP7
    Official Full Name
    mitochondrial 54S ribosomal protein YmL2
    Primary source
    SGD:S000004950
    Locus tag
    YNL005C
    See related
    AllianceGenome:SGD:S000004950; FungiDB:YNL005C; VEuPathDB:YNL005C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    bL27m
    Summary
    A structural constituent of ribosome. Involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL27 (mitochondrial ribosomal protein L27). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRP7 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (621313..622428, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene type II HSP40 co-chaperone SIS1 Neighboring gene TOR complex subunit LST8 Neighboring gene mRNA-binding protein Neighboring gene Pet8p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and regulation of a nuclear gene in Saccharomyces cerevisiae that specifies MRP7, a protein of the large subunit of the mitochondrial ribosome. Fearon K, et al. Mol Cell Biol, 1988 Sep. PMID 2851722, Free PMC Article
    2. The N-terminal region of yeast mitoribosomal Mrp7/bL27m protein serves to optimize translation of nascent chains competent for OXPHOS complex assembly. Anderson JM, et al. FEBS Lett, 2023 Jun. PMID 37115519
    3. Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins. Neuberger G, et al. Genome Biol, 2004. PMID 15575971, Free PMC Article
    4. Nucleotide sequence analysis of an 8887 bp region of the left arm of yeast chromosome XIV, encompassing the centromere sequence. Verhasselt P, et al. Yeast, 1994 Jul. PMID 7985421
    5. Transport of mitoribosomal proteins, YmL13 and MRP7, into isolated mitochondria of Saccharomyces cerevisiae. Matsushita Y, et al. Biochem Mol Biol Int, 1993 Aug. PMID 8220240

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The N-terminal region of yeast mitoribosomal Mrp7/bL27m protein serves to optimize translation of nascent chains competent for OXPHOS complex assembly.
      Title: The N-terminal region of yeast mitoribosomal Mrp7/bL27m protein serves to optimize translation of nascent chains competent for OXPHOS complex assembly.
    2. The mitospecific domain of Mrp7 (bL27) supports mitochondrial translation during fermentation and is required for effective adaptation to respiration.
      Title: The mitospecific domain of Mrp7 (bL27) supports mitochondrial translation during fermentation and is required for effective adaptation to respiration.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL2
    NP_014393.1
    • Mitochondrial ribosomal protein of the large subunit; involved together with Mrpl35p in assembly of cytochrome c oxidase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      621313..622428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182844.1 → NP_014393.1  TPA: mitochondrial 54S ribosomal protein YmL2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014393.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1H2, P12687
      UniProtKB/TrEMBL
      A6ZS71, B3LPP3, B5VR29, C7GJE4, C8ZFM1, G2WL54, N1NWR4
      Conserved Domains (2) summary
      TIGR00062
      Location:27 → 110
      L27; ribosomal protein L27
      pfam18471
      Location:135 → 371
      Ribosomal_L27_C; Ribosomal L27 protein C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P12687.1

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