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    Bod1 biorientation of chromosomes in cell division 1 [ Mus musculus (house mouse) ]

    Gene ID: 69556, updated on 9-Dec-2024

    Summary

    Official Symbol
    Bod1provided by MGI
    Official Full Name
    biorientation of chromosomes in cell division 1provided by MGI
    Primary source
    MGI:MGI:1916806
    See related
    Ensembl:ENSMUSG00000044502 AllianceGenome:MGI:1916806
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bodq1; BOD2.1; Fam44b; 2310022M17Rik
    Summary
    Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Predicted to be involved in cell division. Predicted to be located in centrosome; spindle microtubule; and spindle pole. Predicted to be part of Set1C/COMPASS complex and outer kinetochore. Orthologous to several human genes including BOD1 (biorientation of chromosomes in cell division 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E14 (RPKM 56.8), whole brain E14.5 (RPKM 56.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Bod1 in Genome Data Viewer
    Location:
    11 A4; 11 18.55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (31615150..31621862, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (31665150..31671862, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35012 Neighboring gene predicted gene, 39672 Neighboring gene STARR-seq mESC enhancer starr_29080 Neighboring gene predicted gene, 35063 Neighboring gene STARR-positive B cell enhancer ABC_E137 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:31571987-31572170 Neighboring gene predicted gene, 53678 Neighboring gene predicted gene, 39673

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC144642

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein phosphatase 2A binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Set1C/COMPASS complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    part_of outer kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    biorientation of chromosomes in cell division protein 1
    Names
    biorientation defective protein 1
    bone length and organs 1
    bone length and organs QTL 1
    family with sequence similarity 44, member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024919.1NP_001020090.1  biorientation of chromosomes in cell division protein 1

      See identical proteins and their annotated locations for NP_001020090.1

      Status: PROVISIONAL

      Source sequence(s)
      AK009485, BB616782, BF022873
      Consensus CDS
      CCDS24513.1
      UniProtKB/Swiss-Prot
      Q5SQY2
      UniProtKB/TrEMBL
      Q08EE0
      Related
      ENSMUSP00000056417.8, ENSMUST00000058060.14
      Conserved Domains (1) summary
      pfam05205
      Location:43136
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      31615150..31621862 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)