Zfp35 zinc finger protein 35 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zfp35provided by RGD
Official Full Name: zinc finger protein 35provided by RGD
Primary source: RGD:1312031
See related: EnsemblRapid:ENSRNOG00000049137 AllianceGenome:RGD:1312031
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Zfp239
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 74.6), Brain (RPKM 65.0) and 9 other tissues See more
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Genomic context

Location:: 18p12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (15543604..15559084)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (15268852..15284334)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (15883182..15898803)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in inflammatory response to antigenic stimulus	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of T-helper 2 cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 271

Names: zinc finger protein 239

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013141.2 → NP_001013159.1 zinc finger protein 271

See identical proteins and their annotated locations for NP_001013159.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000018

UniProtKB/TrEMBL

A0A096MJ05, A0A9K3Y763, Q5FVP4

Related

ENSRNOP00000067944.2, ENSRNOT00000076137.4

Conserved Domains (3) summary

COG5048
Location:102 → 486

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:106 → 126

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:230 → 255

zf-H2C2_2; Zinc-finger double domain