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    Prmt7 protein arginine methyltransferase 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361402, updated on 27-Nov-2024

    Summary

    Official Symbol
    Prmt7provided by RGD
    Official Full Name
    protein arginine methyltransferase 7provided by RGD
    Primary source
    RGD:1304869
    See related
    EnsemblRapid:ENSRNOG00000000258 AllianceGenome:RGD:1304869
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304869
    Summary
    Predicted to enable histone binding activity; protein-arginine N-methyltransferase activity; and ribonucleoprotein complex binding activity. Predicted to be involved in peptidyl-arginine methylation; regulation of gene expression; and spliceosomal snRNP assembly. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Orthologous to human PRMT7 (protein arginine methyltransferase 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 128.3), Muscle (RPKM 101.0) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Prmt7 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (51020596..51071401)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (34110724..34161531)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (38189605..38237155)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 member 6 Neighboring gene solute carrier family 7, member 6 opposite strand Neighboring gene sphingomyelin phosphodiesterase 3 Neighboring gene zinc finger protein 90

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone H4 methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone H4R3 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H4R3 methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone H4R3 methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-arginine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-arginine omega-N monomethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-arginine omega-N monomethyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-arginine omega-N symmetric methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-arginine omega-N symmetric methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-arginine omega-N symmetric methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ribonucleoprotein complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribonucleoprotein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in genomic imprinting IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in genomic imprinting ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in genomic imprinting ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidyl-arginine methylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-arginine methylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spliceosomal snRNP assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spliceosomal snRNP assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in fibrillar center IEA
    Inferred from Electronic Annotation
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    protein arginine N-methyltransferase 7
    Names
    [Myelin basic protein]-arginine N-methyltransferase PRMT7
    histone-arginine N-methyltransferase PRMT7
    NP_001014175.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014153.1NP_001014175.1  protein arginine N-methyltransferase 7

      See identical proteins and their annotated locations for NP_001014175.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085121
      UniProtKB/Swiss-Prot
      Q5U4E8
      UniProtKB/TrEMBL
      A0A8L2RAU4
      Related
      ENSRNOP00000075738.3, ENSRNOT00000081312.3
      Conserved Domains (1) summary
      cl17173
      Location:37188
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      51020596..51071401
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)