putative glutamine--fructose-6-phosphate transaminase [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Full Name: putative glutamine--fructose-6-phosphate transaminase
Primary source: SGD:S000004689
Locus tag: YMR084W
See related: AllianceGenome:SGD:S000004689; FungiDB:YMR084W; VEuPathDB:YMR084W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in several processes, including UDP-N-acetylglucosamine metabolic process; chitin biosynthetic process; and protein N-linked glycosylation. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info
enables transaminase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in UDP-N-acetylglucosamine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in UDP-N-acetylglucosamine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in biological_process	ND No biological Data available more info
involved_in chitin biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in fructose 6-phosphate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NP_013801.1

hypothetical protein; YMR084W and adjacent ORF YMR085W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1

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The following sections contain reference sequences that belong to a specific genome build. Explain