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    Samd10 sterile alpha motif domain containing 10 [ Mus musculus (house mouse) ]

    Gene ID: 229011, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Samd10provided by MGI
    Official Full Name
    sterile alpha motif domain containing 10provided by MGI
    Primary source
    MGI:MGI:2443872
    See related
    Ensembl:ENSMUSG00000038605 AllianceGenome:MGI:2443872
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E130318E08; D930033N23Rik
    Summary
    Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side of plasma membrane. Is expressed in nervous system and sensory organ. Orthologous to human SAMD10 (sterile alpha motif domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 37.9), CNS E18 (RPKM 29.7) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Samd10 in Genome Data Viewer
    Location:
    2 H4; 2 103.67 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181237008..181241227, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181595215..181599434, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene uridine-cytidine kinase 1-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E3426 Neighboring gene uridine-cytidine kinase 1-like 1, opposite strand Neighboring gene zinc finger protein 512B Neighboring gene microRNA 7006 Neighboring gene STARR-positive B cell enhancer mm9_chr2:181335875-181336176 Neighboring gene pre-mRNA splicing factor 6 Neighboring gene STARR-seq mESC enhancer starr_06756 Neighboring gene predicted gene, 29797

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sterile alpha motif domain-containing protein 10
    Names
    SAM domain-containing protein 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370751.1 → NP_001357680.1  sterile alpha motif domain-containing protein 10 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL844529
      Conserved Domains (1) summary
      cd09510
      Location:124 → 198
      SAM_aveugle-like; SAM domain of aveugle-like subfamily

    2. NM_172676.3 → NP_766264.2  sterile alpha motif domain-containing protein 10 isoform 1

      See identical proteins and their annotated locations for NP_766264.2

      Status: VALIDATED

      Source sequence(s)
      AL844529
      Consensus CDS
      CCDS17217.1
      UniProtKB/Swiss-Prot
      Q7TST3
      UniProtKB/TrEMBL
      Q3TBN2
      Related
      ENSMUSP00000060499.9, ENSMUST00000060173.9
      Conserved Domains (2) summary
      cd09510
      Location:113 → 187
      SAM_aveugle-like; SAM domain of aveugle-like subfamily
      smart00454
      Location:115 → 182
      SAM; Sterile alpha motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      181237008..181241227 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500607.4 → XP_006500670.1  sterile alpha motif domain-containing protein 10 isoform X1

      Conserved Domains (1) summary
      cd09510
      Location:85 → 159
      SAM_aveugle-like; SAM domain of aveugle-like subfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TST3.1 GenPept UniProtKB/Swiss-Prot:Q7TST3

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