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    Or8g18 olfactory receptor family 8 subfamily G member 18 [ Mus musculus (house mouse) ]

    Gene ID: 257959, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or8g18provided by MGI
    Official Full Name
    olfactory receptor family 8 subfamily G member 18provided by MGI
    Primary source
    MGI:MGI:3031371
    See related
    Ensembl:ENSMUSG00000096109 AllianceGenome:MGI:3031371
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    K4; Olfr144; Olfr1537; MOR171-32P; MOR171-41P; Olfr1537-ps1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or8g18 in Genome Data Viewer
    Location:
    9 A5.1; 9 20.97 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (39148783..39149727, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (39237487..39238431, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily G member 26 Neighboring gene olfactory receptor family 8 subfamily G member 27 Neighboring gene olfactory receptor family 8 subfamily G member 28 Neighboring gene olfactory receptor family 8 subfamily G member 38, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A zonal organization of odorant receptor gene expression in the olfactory epithelium. Ressler KJ, et al. Cell, 1993 May 7. PMID 7683976
    2. Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse. Xie SY, et al. Mamm Genome, 2000 Dec. PMID 11130974
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 8G18
    Names
    GA_x6K02T2PVTD-32935684-32934749
    odorant receptor K4
    olfactory receptor 144
    olfactory receptor 1537, pseudogene 1
    olfactory receptor 7B
    olfactory receptor MOR171-32P
    olfactory receptor MOR171-41P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207665.1 → NP_997548.1  olfactory receptor 8G18

      See identical proteins and their annotated locations for NP_997548.1

      Status: PROVISIONAL

      Source sequence(s)
      AF282288
      Consensus CDS
      CCDS23041.1
      UniProtKB/Swiss-Prot
      P34983, Q7TRB4, Q9EQA1
      UniProtKB/TrEMBL
      A0A1L1SSP9
      Related
      ENSMUSP00000072979.2, ENSMUST00000073248.2
      Conserved Domains (2) summary
      pfam00001
      Location:44 → 293
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:34 → 311
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      39148783..39149727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_001934.1: Suppressed sequence

      Description
      NG_001934.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34983.2 GenPept UniProtKB/Swiss-Prot:P34983

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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