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    Fam117a family with sequence similarity 117, member A [ Mus musculus (house mouse) ]

    Gene ID: 215512, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam117aprovided by MGI
    Official Full Name
    family with sequence similarity 117, member Aprovided by MGI
    Primary source
    MGI:MGI:2144564
    See related
    Ensembl:ENSMUSG00000038893 AllianceGenome:MGI:2144564
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5730593F17Rik
    Summary
    Is expressed in rhombomere 3 and rhombomere 5. Orthologous to human FAM117A (family with sequence similarity 117 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in liver E14.5 (RPKM 25.9), thymus adult (RPKM 23.5) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam117a in Genome Data Viewer
    Location:
    11 D; 11 59.01 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (95227844..95272698)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (95337018..95381872)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9370 Neighboring gene K(lysine) acetyltransferase 7 Neighboring gene STARR-positive B cell enhancer ABC_E9840 Neighboring gene STARR-positive B cell enhancer ABC_E376 Neighboring gene STARR-positive B cell enhancer ABC_E1841 Neighboring gene predicted gene 11520 Neighboring gene STARR-seq mESC enhancer starr_30502 Neighboring gene STARR-positive B cell enhancer ABC_E594 Neighboring gene STARR-positive B cell enhancer ABC_E3009 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:95253828-95254029 Neighboring gene STARR-seq mESC enhancer starr_30505 Neighboring gene solute carrier family 35, member B1 Neighboring gene STARR-positive B cell enhancer ABC_E3010 Neighboring gene STARR-positive B cell enhancer ABC_E10708 Neighboring gene speckle-type BTB/POZ protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain. Chambers D, et al. Neural Dev, 2009 Feb 10. PMID 19208226, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM117A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172543.4 → NP_766131.2  protein FAM117A

      See identical proteins and their annotated locations for NP_766131.2

      Status: VALIDATED

      Source sequence(s)
      AK143632, AK165378, BC055690
      Consensus CDS
      CCDS25276.1
      UniProtKB/Swiss-Prot
      Q3TJJ0, Q3TND5, Q7TNF9, Q8BJY9
      Related
      ENSMUSP00000049162.7, ENSMUST00000037502.7
      Conserved Domains (1) summary
      pfam15388
      Location:86 → 397
      FAM117; Protein Family FAM117

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      95227844..95272698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532835.4 → XP_006532898.1  protein FAM117A isoform X3

      Conserved Domains (1) summary
      pfam15388
      Location:37 → 348
      FAM117; Protein Family FAM117

    2. XM_006532837.3 → XP_006532900.1  protein FAM117A isoform X4

      See identical proteins and their annotated locations for XP_006532900.1

      Conserved Domains (1) summary
      pfam15388
      Location:1 → 259
      FAM117; Protein Family FAM117

    3. XM_006532836.3 → XP_006532899.1  protein FAM117A isoform X4

      See identical proteins and their annotated locations for XP_006532899.1

      Conserved Domains (1) summary
      pfam15388
      Location:1 → 259
      FAM117; Protein Family FAM117

    4. XM_006532834.3 → XP_006532897.3  protein FAM117A isoform X2

      Conserved Domains (1) summary
      pfam15388
      Location:79 → 390
      FAM117; Protein Family FAM117

    5. XM_006532833.5 → XP_006532896.1  protein FAM117A isoform X1

      Conserved Domains (1) summary
      pfam15388
      Location:83 → 394
      FAM117; Protein Family FAM117
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TNF9.1 GenPept UniProtKB/Swiss-Prot:Q7TNF9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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