Nol10 nucleolar protein 10 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nol10provided by MGI
Official Full Name: nucleolar protein 10provided by MGI
Primary source: MGI:MGI:2684913
See related: Ensembl:ENSMUSG00000061458 AllianceGenome:MGI:2684913
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm67
Summary: Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human NOL10 (nucleolar protein 10). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 8.6), CNS E14 (RPKM 5.4) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12 A1.1; 12 8.07 cM

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (17398423..17480101)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (17348421..17430095)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI579107 (e-PCR)
- UniSTS:249352

D4Mit226.1 (e-PCR), detects polymorphism
- UniSTS:130007

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: nucleolar protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008421.1 → NP_001008421.1 nucleolar protein 10

See identical proteins and their annotated locations for NP_001008421.1

Status: PROVISIONAL

Source sequence(s)

BC086676

Consensus CDS

CCDS25828.1

UniProtKB/Swiss-Prot

Q5RJG1

UniProtKB/TrEMBL

Q3TUB5, Q3UFZ4

Related

ENSMUSP00000035930.11, ENSMUST00000046011.12

Conserved Domains (4) summary

COG2319
Location:56 → 312

WD40; WD40 repeat [General function prediction only]

pfam08159
Location:482 → 508

NUC153; NUC153 domain

sd00039
Location:55 → 95

7WD40; WD40 repeat [structural motif]

cl02567
Location:182 → 339

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000078.7 Reference GRCm39 C57BL/6J

Range

17398423..17480101

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017315015.3 → XP_017170504.1 nucleolar protein 10 isoform X1

UniProtKB/TrEMBL

Q3UFZ4

Conserved Domains (4) summary

COG4942
Location:507 → 632

EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]

sd00039
Location:5 → 45

7WD40; WD40 repeat [structural motif]

pfam08159
Location:432 → 458

NUC153; NUC153 domain

cl29593
Location:132 → 289

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...