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    Rnf212b ring finger protein 212B [ Mus musculus (house mouse) ]

    Gene ID: 102632837, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rnf212bprovided by MGI
    Official Full Name
    ring finger protein 212Bprovided by MGI
    Primary source
    MGI:MGI:5589964
    See related
    Ensembl:ENSMUSG00000112858 AllianceGenome:MGI:5589964
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm10332; Gm30805
    Summary
    Enables ubiquitin protein ligase activity. Involved in chiasma assembly and protein ubiquitination. Located in synaptonemal complex. Orthologous to human RNF212B (ring finger protein 212B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in kidney adult (RPKM 2.1), testis adult (RPKM 2.0) and 2 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rnf212b in Genome Data Viewer
    Location:
    14; 14 C2- C3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (55020798..55091567)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (54783341..54854110)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene CCAAT/enhancer binding protein epsilon Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 Neighboring gene STARR-seq mESC enhancer starr_36747 Neighboring gene predicted gene, 17772 Neighboring gene STARR-positive B cell enhancer ABC_E4110 Neighboring gene homeodomain leucine zipper-encoding gene Neighboring gene protein phosphatase 1, regulatory subunit 3E Neighboring gene BCL2-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF212B; rING finger protein 212B
    Names
    RING finger protein C14orf164 homolog
    NP_001357828.1
    XP_006519928.1
    XP_006519930.1
    XP_011243591.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370899.1NP_001357828.1  E3 ubiquitin-protein ligase RNF212B

      Status: VALIDATED

      Source sequence(s)
      AC116591
      Consensus CDS
      CCDS88665.1
      UniProtKB/Swiss-Prot
      D3Z2T6, D3Z423
      Related
      ENSMUSP00000151344.2, ENSMUST00000218311.2
      Conserved Domains (2) summary
      cd16747
      Location:540
      RING-HC_RNF212B; RING finger, HC subclass, found in RING finger protein 212B (RNF212B) and similar proteins
      cl21462
      Location:93124
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      55020798..55091567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245289.3XP_011243591.1  rING finger protein 212B isoform X1

      See identical proteins and their annotated locations for XP_011243591.1

      UniProtKB/Swiss-Prot
      D3Z2T6, D3Z423
      Conserved Domains (2) summary
      cd16747
      Location:540
      RING-HC_RNF212B; RING finger, HC subclass, found in RING finger protein 212B (RNF212B) and similar proteins
      cl21462
      Location:93124
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    2. XM_006519865.3XP_006519928.1  rING finger protein 212B isoform X1

      See identical proteins and their annotated locations for XP_006519928.1

      UniProtKB/Swiss-Prot
      D3Z2T6, D3Z423
      Conserved Domains (2) summary
      cd16747
      Location:540
      RING-HC_RNF212B; RING finger, HC subclass, found in RING finger protein 212B (RNF212B) and similar proteins
      cl21462
      Location:93124
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    3. XM_006519867.4XP_006519930.1  rING finger protein 212B isoform X2

      See identical proteins and their annotated locations for XP_006519930.1

      Conserved Domains (2) summary
      cd16747
      Location:540
      RING-HC_RNF212B; RING finger, HC subclass, found in RING finger protein 212B (RNF212B) and similar proteins
      cl21462
      Location:93124
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain