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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001309297.1 → NP_001296226.1 ATP-sensitive inward rectifier potassium channel 1 isoform 2
See identical proteins and their annotated locations for NP_001296226.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2, also known as ROMK2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2 which has a shorter N-terminus compared to isoform 1.
- Source sequence(s)
-
JAXUCZ010000008
- UniProtKB/Swiss-Prot
- O88639, O88640, P35560, Q9QUR5
- UniProtKB/TrEMBL
- A0A8I6AW52, A6JYI0
- Related
- ENSRNOP00000077878.2, ENSRNOT00000110096.2
- Conserved Domains (1) summary
-
- pfam01007
Location:24 → 352
- IRK; Inward rectifier potassium channel
-
NM_001309298.1 → NP_001296227.1 ATP-sensitive inward rectifier potassium channel 1 isoform 3
See identical proteins and their annotated locations for NP_001296227.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3, also known as ROMK6.1) contains two alternate exons in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3 which has a shorter N-terminus compared to isoform 1. Variants 3, 4 and 5 encode the same protein (isoform 3).
- Source sequence(s)
-
JAXUCZ010000008
- UniProtKB/TrEMBL
- A0A0G2K298, A6JYI4
- Related
- ENSRNOP00000072157.2, ENSRNOT00000081525.3
- Conserved Domains (1) summary
-
- cl21560
Location:1 → 198
- Ion_trans_2; Ion channel
-
NM_001309299.1 → NP_001296228.1 ATP-sensitive inward rectifier potassium channel 1 isoform 3
See identical proteins and their annotated locations for NP_001296228.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4, also known as ROMK3.1) contains three alternate exons in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3 which has a shorter N-terminus compared to isoform 1. Variants 3, 4 and 5 encode the same protein (isoform 3).
- Source sequence(s)
-
JAXUCZ010000008
- UniProtKB/TrEMBL
- A0A0G2K298, A6JYI4
- Related
- ENSRNOP00000078843.2, ENSRNOT00000099372.2
- Conserved Domains (1) summary
-
- cl21560
Location:1 → 198
- Ion_trans_2; Ion channel
-
NM_001309301.1 → NP_001296230.1 ATP-sensitive inward rectifier potassium channel 1 isoform 3
See identical proteins and their annotated locations for NP_001296230.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (5, also known as ROMK1.1) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3 which has a shorter N-terminus compared to isoform 1. Variants 3, 4 and 5 encode the same protein (isoform 3).
- Source sequence(s)
-
JAXUCZ010000008
- UniProtKB/TrEMBL
- A0A0G2K298, A6JYI4
- Conserved Domains (1) summary
-
- cl21560
Location:1 → 198
- Ion_trans_2; Ion channel
-
NM_017023.2 → NP_058719.2 ATP-sensitive inward rectifier potassium channel 1 isoform 1
See identical proteins and their annotated locations for NP_058719.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1, also known as ROMK1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
JAXUCZ010000008
- UniProtKB/Swiss-Prot
- O88639, O88640, P35560, Q9QUR5
- UniProtKB/TrEMBL
- A0A0G2JYW2, A6JYH9
- Related
- ENSRNOP00000070813.1, ENSRNOT00000081614.3
- Conserved Domains (1) summary
-
- pfam01007
Location:43 → 371
- IRK; Inward rectifier potassium channel