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    Eva1a eva-1 homolog A, regulator of programmed cell death [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500221, updated on 27-Nov-2024

    Summary

    Symbol
    Eva1aprovided by RGD
    Full Name
    eva-1 homolog A, regulator of programmed cell deathprovided by RGD
    Primary source
    RGD:1559797
    See related
    EnsemblRapid:ENSRNOG00000007118 AllianceGenome:RGD:1559797
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam176a; Tmem166; RGD1559797
    Summary
    Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Orthologous to human EVA1A (eva-1 homolog A, regulator of programmed cell death). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 81.3), Liver (RPKM 66.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Eva1a in Genome Data Viewer
    Location:
    4q34
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (116151595..116200827)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (114593773..114643011)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (112714023..112823659)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene GC-rich sequence DNA-binding factor 2 Neighboring gene mitochondrial ribosomal protein L19 Neighboring gene peroxiredoxin 6, pseudogene 2 Neighboring gene tachykinin receptor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein eva-1 homolog A
    Names
    family with sequence similarity 176, member A
    protein FAM176A
    transmembrane protein 166

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109243.1NP_001102713.1  protein eva-1 homolog A

      See identical proteins and their annotated locations for NP_001102713.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473957
      UniProtKB/TrEMBL
      A6IAH4, D4A3V0
      Related
      ENSRNOP00000009321.5, ENSRNOT00000009321.7
      Conserved Domains (1) summary
      pfam14851
      Location:20159
      FAM176; FAM176 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      116151595..116200827
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108150.2XP_038964078.1  protein eva-1 homolog A isoform X3

      Conserved Domains (1) summary
      pfam14851
      Location:198
      FAM176; FAM176 family
    2. XM_006236708.5XP_006236770.1  protein eva-1 homolog A isoform X1

      See identical proteins and their annotated locations for XP_006236770.1

      UniProtKB/TrEMBL
      A6IAH4, D4A3V0
      Conserved Domains (1) summary
      pfam14851
      Location:20159
      FAM176; FAM176 family
    3. XM_039108149.2XP_038964077.1  protein eva-1 homolog A isoform X2

      Conserved Domains (1) summary
      pfam14851
      Location:3126
      FAM176; FAM176 family