Yju2 YJU2 splicing factor [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Yju2provided by MGI
Official Full Name: YJU2 splicing factorprovided by MGI
Primary source: MGI:MGI:1920136
See related: Ensembl:ENSMUSG00000003208 AllianceGenome:MGI:1920136
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ccdc94; 2900016D05Rik
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing and negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be part of U2-type catalytic step 1 spliceosome. Is expressed in several structures, including aorta; endocrine gland; genitourinary system; nervous system; and trachea. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 6.6), CNS E14 (RPKM 5.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 17 D; 17 29.08 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (56266187..56274951)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (55959187..55967951)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in RNA splicing	IBA Inferred from Biological aspect of Ancestor more info
involved_in generation of catalytic spliceosome for first transesterification step	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of DNA damage response, signal transduction by p53 class mediator	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of U2-type catalytic step 1 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type catalytic step 1 spliceosome	ISO Inferred from Sequence Orthology more info
part_of U2-type catalytic step 1 spliceosome	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: splicing factor YJU2

Names: YJU2 splicing factor homolog; coiled-coil domain containing 94; coiled-coil domain-containing protein 94

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_028381.3 → NP_082657.1 splicing factor YJU2

See identical proteins and their annotated locations for NP_082657.1

Status: PROVISIONAL

Source sequence(s)

BC031400

Consensus CDS

CCDS37660.1

UniProtKB/Swiss-Prot

Q9D6J3

Related

ENSMUSP00000084082.5, ENSMUST00000086869.6

Conserved Domains (2) summary

COG5134
Location:7 → 156

COG5134; Uncharacterized conserved protein [Function unknown]

pfam04502
Location:8 → 261

DUF572; Family of unknown function (DUF572)