U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rab26 RAB26, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 328778, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rab26provided by MGI
    Official Full Name
    RAB26, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:2443284
    See related
    Ensembl:ENSMUSG00000079657 AllianceGenome:MGI:2443284
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A830020M03Rik
    Summary
    Predicted to enable GMP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in several processes, including Golgi to plasma membrane protein transport; exocrine system development; and regulation protein catabolic process at presynapse. Located in secretory granule membrane. Orthologous to human RAB26 (RAB26, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 24.6), cortex adult (RPKM 21.7) and 4 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rab26 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.4 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24748038..24752696, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24529054..24533747, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene CASK interacting protein 1 Neighboring gene TNF receptor-associated factor 7 Neighboring gene STARR-positive B cell enhancer ABC_E33 Neighboring gene RAB26, member RAS oncogene family, opposite strand Neighboring gene small nucleolar RNA, C/D box 60 Neighboring gene predicted gene, 33508 Neighboring gene STARR-positive B cell enhancer ABC_E1189 Neighboring gene predicted gene, 57643 Neighboring gene polycystin 1, transient receptor potential channel interacting

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GMP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GMP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Golgi to plasma membrane protein transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in exocrine system development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in exocrine system development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulated exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulated exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation protein catabolic process at presynapse ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in secretory granule membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in transport vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177375.2NP_796349.1  ras-related protein Rab-26

      See identical proteins and their annotated locations for NP_796349.1

      Status: VALIDATED

      Source sequence(s)
      AC132367
      Consensus CDS
      CCDS50016.1
      UniProtKB/Swiss-Prot
      Q504M8
      UniProtKB/TrEMBL
      H3BLG3, Q0PD29, Q148R0
      Related
      ENSMUSP00000046089.10, ENSMUST00000035797.16
      Conserved Domains (2) summary
      smart00175
      Location:68232
      RAB; Rab subfamily of small GTPases
      cd04112
      Location:68258
      Rab26; Rab GTPase family 26 (Rab26)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      24748038..24752696 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)