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    Syngr3 synaptogyrin 3 [ Mus musculus (house mouse) ]

    Gene ID: 20974, updated on 9-Dec-2024

    Summary

    Official Symbol
    Syngr3provided by MGI
    Official Full Name
    synaptogyrin 3provided by MGI
    Primary source
    MGI:MGI:1341881
    See related
    Ensembl:ENSMUSG00000007021 AllianceGenome:MGI:1341881
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Enables SH2 domain binding activity. Involved in positive regulation of transporter activity; regulated exocytosis; and regulation of synaptic vesicle priming. Located in synapse. Is active in neuromuscular junction and synaptic vesicle. Is expressed in several structures, including central nervous system; eye; and peripheral nervous system ganglion. Orthologous to human SYNGR3 (synaptogyrin 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 49.6), frontal lobe adult (RPKM 44.3) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Syngr3 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.47 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24904066..24908923, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24685092..24689949, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene neuropeptide W Neighboring gene zinc finger protein 598 Neighboring gene STARR-positive B cell enhancer ABC_E11630 Neighboring gene growth factor, augmenter of liver regeneration Neighboring gene NADPH oxidase organizer 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5)  1 citation
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH2 domain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in neuromuscular junction IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic vesicle IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synaptic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    synaptogyrin-3
    Names
    Sgyr III
    synaptogryin III

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011522.3NP_035652.2  synaptogyrin-3

      See identical proteins and their annotated locations for NP_035652.2

      Status: PROVISIONAL

      Source sequence(s)
      AK081164
      Consensus CDS
      CCDS28491.1
      UniProtKB/Swiss-Prot
      Q8R191, Q9WVG8
      Related
      ENSMUSP00000007236.5, ENSMUST00000007236.5
      Conserved Domains (1) summary
      pfam01284
      Location:20165
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      24904066..24908923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)