ALG2 ALG2 alpha-1,3/1,6-mannosyltransferase [Sus scrofa (pig)] - Gene

Summary

Official Symbol: ALG2provided by VGNC
Official Full Name: ALG2 alpha-1,3/1,6-mannosyltransferaseprovided by VGNC
Primary source: VGNC:VGNC:85250
See related: Ensembl:ENSSSCG00000005383
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Ubiquitous expression in kidney (RPKM 4.2), ovary (RPKM 2.7) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	1	NC_010443.5 (240973022..240984816, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	1	NC_010443.4 (269210057..269215674, complement)

Chromosome 1 - NC_010443.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables alpha-1,3-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alpha-1,3/1,6-mannosyltransferase ALG2

Names: asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog

NP_001094499.1

EC 2.4.1.132

EC 2.4.1.257

XP_013849144.1

EC 2.4.1.132

EC 2.4.1.257

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101029.1 → NP_001094499.1 alpha-1,3/1,6-mannosyltransferase ALG2

See identical proteins and their annotated locations for NP_001094499.1

Status: PROVISIONAL

Source sequence(s)

AY683050

UniProtKB/TrEMBL

A0A480LCC4, A0A8D1A0Z9, A7E1U0

Related

ENSSSCP00000005776.2, ENSSSCT00000005923.5

Conserved Domains (2) summary

cd03805
Location:16 → 407

GT1_ALG2_like; This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2) ...

COG0438
Location:17 → 415

RfaB; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010443.5 Reference Sscrofa11.1 Primary Assembly

Range

240973022..240984816 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_013993690.2 → XP_013849144.1 alpha-1,3/1,6-mannosyltransferase ALG2 isoform X1

Conserved Domains (2) summary

COG0438
Location:53 → 347

RfaB; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]

cl10013
Location:25 → 339

Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...