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    Dnah7b dynein, axonemal, heavy chain 7B [ Mus musculus (house mouse) ]

    Gene ID: 227058, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dnah7bprovided by MGI
    Official Full Name
    dynein, axonemal, heavy chain 7Bprovided by MGI
    Primary source
    MGI:MGI:2684953
    See related
    Ensembl:ENSMUSG00000041144 AllianceGenome:MGI:2684953
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm107; Dnahc7b
    Summary
    Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility. Predicted to act upstream of or within cilium movement and inner dynein arm assembly. Predicted to be located in cytosol. Predicted to be part of inner dynein arm. Predicted to be active in 9+2 motile cilium. Is expressed in spermatozoon and testis. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human DNAH7 (dynein axonemal heavy chain 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 4.9), CNS E14 (RPKM 0.9) and 7 other tissues See more
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    Genomic context

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    See Dnah7b in Genome Data Viewer
    Location:
    1 C1.1; 1 23.96 cM
    Exon count:
    76
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (46105232..46412711)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (46066071..46373551)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase 2 Neighboring gene asparagine synthetase domain containing 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_00825 Neighboring gene predicted gene, 31046 Neighboring gene STARR-seq mESC enhancer starr_00826 Neighboring gene STARR-seq mESC enhancer starr_00827 Neighboring gene STARR-seq mESC enhancer starr_00828 Neighboring gene nuclear encoded rRNA 5S 211 Neighboring gene heat shock protein 8 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. Dong F, et al. J Cell Biol, 2014 Jan 20. PMID 24421334, Free PMC Article
    2. Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. Neesen J, et al. Gene, 1997 Oct 24. PMID 9373155
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dynein light intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables minus-end-directed microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cilium movement ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium movement involved in cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within inner dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in 9+2 motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of inner dynein arm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of inner dynein arm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    dynein, axonemal, heavy chain 7B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368717.1 → NP_001355646.1  dynein, axonemal, heavy chain 7B

      Status: VALIDATED

      Source sequence(s)
      AC108850, AC122879, AC125310
      Consensus CDS
      CCDS87825.1
      UniProtKB/TrEMBL
      A0A571BD48, L7N1Y0
      Related
      ENSMUSP00000158612.2, ENSMUST00000238212.2
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3666
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2963 → 3179
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3720 → 4020
      Dynein_C; Dynein heavy chain C-terminal domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      46105232..46412711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011238490.4 → XP_011236792.1  dynein, axonemal, heavy chain 7B isoform X1

      See identical proteins and their annotated locations for XP_011236792.1

      UniProtKB/TrEMBL
      A0A571BD48, L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3666
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2963 → 3179
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3720 → 4020
      Dynein_C; Dynein heavy chain C-terminal domain

    2. XM_006495931.5 → XP_006495994.1  dynein, axonemal, heavy chain 7B isoform X19

      Conserved Domains (6) summary
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12775
      Location:1938 → 2118
      AAA_7; P-loop containing dynein motor region D3
      pfam17852
      Location:1782 → 1929
      Dynein_AAA_lid; Dynein heavy chain AAA lid domain
      pfam17857
      Location:2152 → 2211
      AAA_lid_1; AAA+ lid domain
      cl38936
      Location:1604 → 1747
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_006495929.5 → XP_006495992.1  dynein, axonemal, heavy chain 7B isoform X17

      Conserved Domains (6) summary
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12775
      Location:1938 → 2118
      AAA_7; P-loop containing dynein motor region D3
      pfam17852
      Location:1782 → 1929
      Dynein_AAA_lid; Dynein heavy chain AAA lid domain
      pfam17857
      Location:2152 → 2211
      AAA_lid_1; AAA+ lid domain
      cl38936
      Location:1604 → 1747
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_006495930.5 → XP_006495993.1  dynein, axonemal, heavy chain 7B isoform X18

      Conserved Domains (6) summary
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12775
      Location:1938 → 2118
      AAA_7; P-loop containing dynein motor region D3
      pfam17852
      Location:1782 → 1929
      Dynein_AAA_lid; Dynein heavy chain AAA lid domain
      pfam17857
      Location:2152 → 2211
      AAA_lid_1; AAA+ lid domain
      cl38936
      Location:1604 → 1747
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. XM_011238495.4 → XP_011236797.1  dynein, axonemal, heavy chain 7B isoform X13

      Conserved Domains (8) summary
      pfam12777
      Location:2587 → 2866
      MT; Microtubule-binding stalk of dynein motor
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12775
      Location:1938 → 2118
      AAA_7; P-loop containing dynein motor region D3
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam17852
      Location:1782 → 1929
      Dynein_AAA_lid; Dynein heavy chain AAA lid domain
      pfam17857
      Location:2152 → 2247
      AAA_lid_1; AAA+ lid domain
      cl38936
      Location:1604 → 1747
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. XM_006495928.5 → XP_006495991.1  dynein, axonemal, heavy chain 7B isoform X15

      Conserved Domains (8) summary
      pfam12777
      Location:2587 → 2686
      MT; Microtubule-binding stalk of dynein motor
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12775
      Location:1938 → 2118
      AAA_7; P-loop containing dynein motor region D3
      pfam12780
      Location:2311 → 2573
      AAA_8; P-loop containing dynein motor region D4
      pfam17852
      Location:1782 → 1929
      Dynein_AAA_lid; Dynein heavy chain AAA lid domain
      pfam17857
      Location:2152 → 2247
      AAA_lid_1; AAA+ lid domain
      cl38936
      Location:1604 → 1747
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    7. XM_011238494.4 → XP_011236796.1  dynein, axonemal, heavy chain 7B isoform X12

      Conserved Domains (9) summary
      pfam12777
      Location:2587 → 2933
      MT; Microtubule-binding stalk of dynein motor
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12775
      Location:1938 → 2118
      AAA_7; P-loop containing dynein motor region D3
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2963 → 3033
      AAA_9; ATP-binding dynein motor region D5
      pfam17852
      Location:1782 → 1929
      Dynein_AAA_lid; Dynein heavy chain AAA lid domain
      pfam17857
      Location:2152 → 2247
      AAA_lid_1; AAA+ lid domain
      cl38936
      Location:1604 → 1747
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    8. XM_006495925.5 → XP_006495988.1  dynein, axonemal, heavy chain 7B isoform X11

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (5) summary
      COG5245
      Location:797 → 3666
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2963 → 3179
      AAA_9; ATP-binding dynein motor region D5

    9. XM_006495915.5 → XP_006495978.1  dynein, axonemal, heavy chain 7B isoform X4

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3610
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2963 → 3179
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3658 → 3958
      Dynein_C; Dynein heavy chain C-terminal domain

    10. XM_006495916.5 → XP_006495979.1  dynein, axonemal, heavy chain 7B isoform X6

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3591
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2236 → 2496
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2888 → 3104
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3645 → 3945
      Dynein_C; Dynein heavy chain C-terminal domain

    11. XM_006495913.5 → XP_006495976.1  dynein, axonemal, heavy chain 7B isoform X2

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3633
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1583
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2278 → 2538
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2930 → 3146
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3687 → 3987
      Dynein_C; Dynein heavy chain C-terminal domain

    12. XM_036164345.1 → XP_036020238.1  dynein, axonemal, heavy chain 7B isoform X5

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3595
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1219 → 1545
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2240 → 2502
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2892 → 3108
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3649 → 3949
      Dynein_C; Dynein heavy chain C-terminal domain

    13. XM_006495914.5 → XP_006495977.1  dynein, axonemal, heavy chain 7B isoform X3

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3619
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1160
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1243 → 1569
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2264 → 2524
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2916 → 3132
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3673 → 3973
      Dynein_C; Dynein heavy chain C-terminal domain

    14. XM_030253646.2 → XP_030109506.1  dynein, axonemal, heavy chain 7B isoform X8

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:618 → 3487
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:578 → 983
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1111 → 1437
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2132 → 2392
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2784 → 3000
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3541 → 3841
      Dynein_C; Dynein heavy chain C-terminal domain

    15. XM_030253644.2 → XP_030109504.1  dynein, axonemal, heavy chain 7B isoform X7

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:711 → 3580
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:671 → 1076
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1204 → 1530
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2225 → 2485
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2877 → 3093
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3634 → 3934
      Dynein_C; Dynein heavy chain C-terminal domain

    16. XM_030253647.2 → XP_030109507.1  dynein, axonemal, heavy chain 7B isoform X8

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:618 → 3487
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:578 → 983
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1111 → 1437
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2132 → 2392
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2784 → 3000
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3541 → 3841
      Dynein_C; Dynein heavy chain C-terminal domain

    17. XM_011238487.4 → XP_011236789.1  dynein, axonemal, heavy chain 7B isoform X1

      See identical proteins and their annotated locations for XP_011236789.1

      UniProtKB/TrEMBL
      A0A571BD48, L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:797 → 3666
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:757 → 1162
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1290 → 1616
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2311 → 2571
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2963 → 3179
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3720 → 4020
      Dynein_C; Dynein heavy chain C-terminal domain

    18. XM_006495920.2 → XP_006495983.1  dynein, axonemal, heavy chain 7B isoform X8

      See identical proteins and their annotated locations for XP_006495983.1

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:618 → 3487
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:578 → 983
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1111 → 1437
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2132 → 2392
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2784 → 3000
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3541 → 3841
      Dynein_C; Dynein heavy chain C-terminal domain

    19. XM_006495921.2 → XP_006495984.1  dynein, axonemal, heavy chain 7B isoform X8

      See identical proteins and their annotated locations for XP_006495984.1

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:618 → 3487
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:578 → 983
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1111 → 1437
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2132 → 2392
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2784 → 3000
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3541 → 3841
      Dynein_C; Dynein heavy chain C-terminal domain

    20. XM_011238492.4 → XP_011236794.1  dynein, axonemal, heavy chain 7B isoform X9

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:601 → 3470
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:561 → 966
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1094 → 1420
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2115 → 2375
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2767 → 2983
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3524 → 3824
      Dynein_C; Dynein heavy chain C-terminal domain

    21. XM_006495923.1 → XP_006495986.1  dynein, axonemal, heavy chain 7B isoform X10

      UniProtKB/TrEMBL
      L7N1Y0
      Conserved Domains (6) summary
      COG5245
      Location:549 → 3418
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:509 → 914
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1042 → 1368
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:2063 → 2323
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:2715 → 2931
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:3472 → 3772
      Dynein_C; Dynein heavy chain C-terminal domain

    22. XM_030253671.1 → XP_030109531.1  dynein, axonemal, heavy chain 7B isoform X16

      Conserved Domains (5) summary
      COG5245
      Location:36 → 2339
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam12774
      Location:18 → 289
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:984 → 1246
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:1636 → 1852
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:2393 → 2693
      Dynein_C; Dynein heavy chain C-terminal domain

    23. XM_011238496.2 → XP_011236798.1  dynein, axonemal, heavy chain 7B isoform X14

      See identical proteins and their annotated locations for XP_011236798.1

      Conserved Domains (5) summary
      COG5245
      Location:36 → 2372
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam12774
      Location:18 → 322
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:1017 → 1279
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:1669 → 1885
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:2426 → 2726
      Dynein_C; Dynein heavy chain C-terminal domain

    24. XM_006495927.3 → XP_006495990.1  dynein, axonemal, heavy chain 7B isoform X14

      See identical proteins and their annotated locations for XP_006495990.1

      Conserved Domains (5) summary
      COG5245
      Location:36 → 2372
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam12774
      Location:18 → 322
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam12780
      Location:1017 → 1279
      AAA_8; P-loop containing dynein motor region D4
      pfam12781
      Location:1669 → 1885
      AAA_9; ATP-binding dynein motor region D5
      pfam18199
      Location:2426 → 2726
      Dynein_C; Dynein heavy chain C-terminal domain

    RNA

    1. XR_003954985.2 RNA Sequence

    2. XR_003954980.2 RNA Sequence

    3. XR_373250.5 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001160386.1: Suppressed sequence

      Description
      NM_001160386.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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